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Test Code PDLPNL PEDIATRIC LIVER PANEL

Important Note

This order is for Pediatric samples ONLY.

Specimen and Container/Tube

Specimen Type: Plasma

Preferred Specimen: Li-Heparin Mint Green Top

Other Acceptable specimens: Serum/Gold Top, Serum/Red Top

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Make sure sample is tightly capped.
  • Samples must be sent room temperature at 15-25oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

 

Test

Age

Sex

Reference Range

Total Protein

All

All

6.0-8.3 mg/dL

Albumin

All

All

3.5-5.0 mg/dL

BILT

0-1 Days

ALL

1.0-6.0 mg/dL

BILT

1-2 Days

ALL

2.0-8.0 mg/dL

BILT

3-5 Days

ALL

4.0-12.0 mg/dL

BILT

6-14 Days

ALL

0.6-7.0 mg/dL

BILT

≥15 Days

ALL

0.1-1.0 mg/dL

PEDBC

0-13 Days

ALL

0.0 - 0.6 mg/dL

PEDBC

≥14 Days

ALL

0.0-0.3 mg/dL

BU

0-1 Days

ALL

1.0-6.0 mg/dL

BU

1-2 Days

ALL

2.0-8.0 mg/dL

BU

3-5 Days

ALL

4.0-12.0 mg/dL

BU

6-14 Days

ALL

0.6-7.0 mg/dL

BU

≥15 Days

ALL

0.1-1.0 mg/dL

ALKP

0-1 Months

Unspecified

150 - 420 U/L

ALKP

1 Month - 19 Years

Unspecified

100 - 390 U/L

ALKP

19 - 61 Years

Unspecified

30 - 120 U/L

ALKP

61 Years - Unspecified

Unspecified

50 - 150 mg/dL

AST (GOT)

All

All

8 - 37 U/L

ALT (GPT)

All

All

8-35 U/L

Note: Reference range based on in-house studies, recommendations from Tietz Textbook of Clinical Chemistry, and Roche product literature. 

Critical Values

Analyte

Unit

Low

High

Age

BILT

mg/dL

NA

18.0

≤ 14 days

CPT Codes

80076 - LPNL

Individual CPT:

Bilt - 82247

Total Protein - 84155

Albumin - 82040

AST - 84450

Alkaline Phosphatase - 84075

ALT - 84460

PEDBC - 82248

 

LOINC Codes

LFT: 24325-3

Components:

1751-7 Albumin

6768-6 Alkaline Phosphatase

1743-4 Alanine Aminotransferase

30239-8 Aspartate Amino transferase (AST)

1975-2 Bilirubin, Total

1968-7 Pediatric Bilirubin (Conjugated)

2885-2 Total Protein

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Refrigerated

7 Days

Frozen

N/A

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Test Components

 

  • Total Bilirubin
  • Conjugated Bilirubin (Pediatric)
  • Unconjugated Bilirubin
  • Total Protein
  • Albumin
  • Alkaline Phosphatase
  • Aspartate Aminotransferase (AST)
  • Alanine Aminotransferase (ALT)

Clinical Indications

  • The hepatic function panel may be used to help diagnose liver disease if a person has signs and symptoms that indicate possible liver dysfunction. If a person has a known condition or liver disease, testing may be performed at intervals to monitor the health of the liver and to evaluate the effectiveness of any treatments. Abnormal tests on a liver panel may prompt a repeat analysis of one or more tests, or of the whole panel, to see if the elevations or decreases persist and may indicate the need for additional testing to determine the cause of the liver dysfunction.

Methodology

BILT: Photometric, Diazonium Salt (Roche Diagnostics)

PEDBC: Photometric, Vanadate Oxidation (Randox)

AST: Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate (Roche Diagnostics)

ALT: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate (Roche Diagnostics)

ALP: Photometric, p-Nitrophenol Phosphate (Roche Diagnostics)

ALB: Photometric, Bromcresol Green (Roche Diagnostics)

TP: Colorimetric, Biuret (Roche Diagnostics)

Additional Information

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Last Review Date

08/06/2024