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Mayo Clinic Laboratories

Test Code TP Total Protein

Specimen and Container/Tube

Specimen Type: Plasma

Preferred Specimen: Li-Heparin Mint Green Top

Other Acceptable specimens: Serum/Gold Top, Serum/Red Top, Plasma/Lavendar K2 Top

Specimen Stability

Storage Temperature

Stability

Room temperature

6 days

Refrigerated

4 weeks

Frozen

1 year

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent room temperature at 15-25oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

 

Test

Age

Sex

Reference Range

Total Protein

All

All

6.0-8.3 g/dL

Critical Values

Not applicable 

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Clinical Indications

Total protein measurements are used in the diagnosis and treatment of a variety of diseases involving the liver, kidney or bone marrow, as well as other metabolic or nutritional disorders.

Test Components

Total Protein

Methodology

Endpoint Colorimetric Assay Spectrophotometric (Roche Diagnostics)

CPT Codes

84155

LOINC Codes

2885-2

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • The total protein concentration is 0.4 to 0.8 g/dL lower when the sample is collected from a patient situated in the recumbent position rather than upright.

Last Review Date

8/19/2024

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL