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HelpTest Code LPNL HEPATIC FUNCTION PANEL
Specimen and Container/Tube
Specimen Type: Plasma
Preferred Specimen: Li-Heparin Mint Green Top
Other Acceptable specimens: Serum/Gold Top, Serum/Red Top
Specimen Handling and Transport Instructions
UCMC Onsite Instructions:
Collect specimen per standard collection procedure and send to laboratory immediately.
UCMC Offsite and UC MedLab Outreach Instructions:
- Samples should be centrifuged within 2 hours of collection.
- Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
- Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
- Make sure sample is tightly capped.
- Samples must be sent room temperature at 15-25oC.
Rejection Criteria
- Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits.
- Specimens that are clotted or grossly hemolyzed.
- Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.
Reference Values
|
Test |
Age |
Sex |
Reference Range |
|
Total Protein |
All |
All |
6.0-8.3 mg/dL |
|
Albumin |
All |
All |
3.5-5.0 mg/dL |
|
BILT |
0-1 Days |
ALL |
1.0-6.0 mg/dL |
|
BILT |
1-2 Days |
ALL |
2.0-8.0 mg/dL |
|
BILT |
3-5 Days |
ALL |
4.0-12.0 mg/dL |
|
BILT |
6-14 Days |
ALL |
0.6-7.0 mg/dL |
|
BILT |
≥15 Days |
ALL |
0.1-1.0 mg/dL |
|
BC |
0-14 Days |
ALL |
0.0 - 0.6 mg/dL |
|
BC |
≥15 Days |
ALL |
0.0-0.3 mg/dL |
|
BU |
0-1 Days |
ALL |
1.0-6.0 mg/dL |
|
BU |
1-2 Days |
ALL |
2.0-8.0 mg/dL |
|
BU |
3-5 Days |
ALL |
4.0-12.0 mg/dL |
|
BU |
6-14 Days |
ALL |
0.6-7.0 mg/dL |
|
BU |
≥15 Days |
ALL |
0.1-1.0 mg/dL |
|
ALKP |
0-1 Months |
Unspecified |
150 - 420 U/L |
|
ALKP |
1 Month - 19 Years |
Unspecified |
100 - 390 U/L |
|
ALKP |
19 - 61 Years |
Unspecified |
30 - 120 U/L |
|
ALKP |
61 Years - Unspecified |
Unspecified |
50 - 150 mg/dL |
|
AST (GOT) |
All |
All |
8 - 37 U/L |
|
ALT (GPT) |
All |
All |
8-35 U/L |
Note: Reference range based on in-house studies, recommendations from Tietz Textbook of Clinical Chemistry, and Roche product literature.
Critical Values
|
Analyte |
Unit |
Low |
High |
Age |
|
BILT |
mg/dL |
NA |
18.0 |
≤ 14 days |
CPT Codes
80076 - LPNL
Individual CPT:
Bilt - 82247
Total Protein - 84155
Albumin - 82040
AST - 84450
Alkaline Phosphatase - 84075
ALT - 84460
BC - 82248
LOINC Codes
LFT: 24325-3
Components:
1751-7 Albumin
6768-6 Alkaline Phosphatase
1743-4 Alanine Aminotransferase
30239-8 Aspartate Amino transferase (AST)
1975-2 Bilirubin, Total
1968-7 Bilirubin (Conjugated)
2885-2 Total Protein
Volume
Preferred Volume: 0.5 mL
Minimum Volume: 0.2 mL
Specimen Stability
|
Storage Temperature |
Stability |
|
Refrigerated |
7 Days |
|
Frozen |
N/A |
Collection Instructions
Collect specimen per standard laboratory collection procedures.
Test Components
- Total Bilirubin
- Conjugated Bilirubin
- Unconjugated Bilirubin
- Total Protein
- Albumin
- Alkaline Phosphatase
- Aspartate Aminotransferase (AST)
- Alanine Aminotransferase (ALT)
Clinical Indications
- The hepatic function panel may be used to help diagnose liver disease if a person has signs and symptoms that indicate possible liver dysfunction. If a person has a known condition or liver disease, testing may be performed at intervals to monitor the health of the liver and to evaluate the effectiveness of any treatments. Abnormal tests on a liver panel may prompt a repeat analysis of one or more tests, or of the whole panel, to see if the elevations or decreases persist and may indicate the need for additional testing to determine the cause of the liver dysfunction.
Methodology
BILT: Photometric, Diazonium Salt (Roche Diagnostics)
BC: Photometric, Diazotized Sulfanilic Acid (Roche Diagnostics)
AST: Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate (Roche Diagnostics)
ALT: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate (Roche Diagnostics)
ALP: Photometric, p-Nitrophenol Phosphate (Roche Diagnostics)
ALB: Photometric, Bromcresol Green (Roche Diagnostics)
TP: Colorimetric, Biuret (Roche Diagnostics)
Additional Information
- Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
- For Additional Information please see individual test. Total Bilirubin, Total Protein, Albumin, Alkaline Phosphatase, Aspartate Aminotransferase (AST), Alanine Aminotransferase (AST), Conjugated Bilirubin
- Each of these test components may be ordered individually. A test or panel may be ordered only when all components are medically necessary to diagnose or treat an individual patient. If all components are not medically necessary, a less inclusive panel and/or an individual test as appropriate to treat the individual patient should be ordered.
Turnaround Time
Turnaround times are relative to the time the specimen is received in the test laboratory.
STAT Turnaround Time: 1 hour
Routine Turnaround Time: 4 hours
Testing Schedule: 24/7
Synonyms/Keyword Search
Total Protein, Total Bilirubin, AST, ALT, Alanine Aminotransferase, Aspartate Aminotransferase, Albumin, Alkaline Phosphatase, Liver Function Panel, ER Panel II
Last Review Date
08/06/2024