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HelpTest Code SIRB Sirolimus
Specimen Type
Whole Blood
Container/Tube
EDTA Lavendar Top
Offsite Collection Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport room temperature (15 – 25C).
Turnaround Time
N/A
Test Includes
N/A
Preferred Volume
4.0 mL
Microcontainer =0.5 mL
UCMC Collection Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport room temperature (15 – 25C).
Test Usage
Monitoring whole blood sirolimus concentration during
therapy.
Critical Results
N/A
Test Limitations
N/A
Additional Information
This test was developed and its performance characteristics
determined by The University of Chicago Medical Center Clinical
Chemistry Laboratories in a manner consistent with CLIA requirements. This
test has not been cleared or
approved by the U.S. Food and Drug Administration.
Specimen Minimum Volume
2.0 mL
Microcontainer =0.25 mL
Day(s) Performed
Monday – Friday (7am – 3pm)
Saturday & Sunday (7am – 9am)
STAT DAY(S) AND TIME(S) PERFORMED
N/A
Method Name
Liquid Chromatography/Mass Spectometry
(LC-MS/MS)
Reference Values
3 �?? 20 ng/mL
Therapeutic (reference) ranges for immunosuppressant drugs
have
generally not been well established, as these tend to vary
depending on the type of transplant, patient clinical status
and
post-transplant duration/course, concomitant use of other
pharmacologic agents of the same class, the dosing/collection
intervals and other known factors. This range is based upon
commonly published guidelines, and any results are subject to
physician interpretation and should be used in conjunction with
other diagnostic and clinical information.
Reject Due To
N/A
STAT Turnaround Time
N/A
Included in Additional codes
N/A
Coverage Information
N/A
Stability: Room Temp
7 days
Stability: Refrigerated
7 days
Stability: Frozen
3 months
Specimen and Container/Tube
Whole Blood
Pediatric Volume
2.0 mL
Microcontainer =0.25 mL
Clinical Indications
Monitoring whole blood sirolimus concentration during
therapy.
Transport Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport?�room temperature (15 �?? 25C).
Test Components
N/A
Specimen Stability
7 days
Rejection Criteria
N/A
Methodology
Liquid Chromatography/Mass Spectometry
(LC-MS/MS)