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HelpTest Code SIRB Sirolimus
Specimen and Container/Tube
Whole Blood
Rejection Criteria
N/A
Turnaround Time
N/A
Test Includes
N/A
Specimen Type
Whole Blood
Preferred Volume
4.0 mL
Microcontainer =0.5 mL
Offsite Collection Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport room temperature (15 – 25C).
UCMC Collection Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport room temperature (15 – 25C).
Test Usage
Monitoring whole blood sirolimus concentration during
therapy.
Critical Results
N/A
Test Limitations
N/A
Additional Information
This test was developed and its performance characteristics
determined by The University of Chicago Medical Center Clinical
Chemistry Laboratories in a manner consistent with CLIA requirements. This
test has not been cleared or
approved by the U.S. Food and Drug Administration.
Container/Tube
EDTA Lavendar Top
Specimen Minimum Volume
2.0 mL
Microcontainer =0.25 mL
Day(s) Performed
Monday – Friday (7am – 3pm)
Saturday & Sunday (7am – 9am)
STAT DAY(S) AND TIME(S) PERFORMED
N/A
Method Name
Liquid Chromatography/Mass Spectometry
(LC-MS/MS)
Reference Values
3 - 20 ng/mL
Therapeutic (reference) ranges for immunosuppressant drugs have generally not been well established, as these tend to vary depending on the type of transplant, patient clinical status and post-transplant duration/course, concomitant use of other
pharmacologic agents of the same class, the dosing/collection intervals and other known factors. This range is based upon
commonly published guidelines, and any results are subject to physician interpretation and should be used in conjunction with other diagnostic and clinical information.
Reject Due To
N/A
STAT Turnaround Time
N/A
Included in Additional codes
N/A
Coverage Information
N/A
Stability: Room Temp
7 days
Stability: Refrigerated
7 days
Stability: Frozen
3 months
Pediatric Volume
2.0 mL
Microcontainer =0.25 mL
Clinical Indications
Monitoring whole blood sirolimus concentration during
therapy.
Transport Instructions
1. Collect sample following standard collection methods
immediately before scheduled dose.
2. Transport?�room temperature (15 �?? 25C).
Test Components
N/A
Specimen Stability
7 days
Methodology
Liquid Chromatography/Mass Spectometry
(LC-MS/MS)