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Test Code RPAGG Ristocetin Induced Platelet Aggregation (RIPA)

Important Note

Test must be scheduled with Coagulation Laboratory. Please call 773-702-1315 (2-1315).

Coagulation Lab Staff must be present for sample collection.

Specimen cannot be collected offsite; patient specimen must be drawn at Hyde Park location.

Specimen and Container/Tube

Specimen Type: Whole Blood

Preferred Specimen: Light Blue Top Tube, 3.2% Sodium Citrate

Other Acceptable specimens: N/A

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

1. Coagulation Lab Staff must be present for sample collection. Please call Coagulation lab at 773-702-1315 (2-1315).

2. Specimens may not be sent to the lab via the Pneumatic tube station (PTS).

 

UCMC Offsite and UC MedLab Outreach Instructions: 

Specimen cannot be collected offsite; patient specimen must be drawn at Hyde Park location.

Test must be scheduled with Coagulation Laboratory.

Please call 773-702-1315.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens collected off-site and sent to Coagulation laboratory will be rejected

Reference Values

 

Test

Age

Sex

Reference Range

Decreasing doses of Ristocetin

ALL

ALL

Interpretation provided

Critical Values

Analyte

Unit

Low

High

Age

N/A

N/A

N/A

N/A

N/A

CPT Codes

85576 X5

LOINC Codes

5998-0

Volume

Preferred Volume: Ten Light Blue Top Tubes, 3.2% Sodium Citrate

 

Minimum Volume: Ten Light Blue Top Tubes, 3.2% Sodium Citrate

Specimen Stability

Storage Temperature

Stability

Room temperature

4 hours

Refrigerated

not acceptable

Frozen

not acceptable

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

NOTE: Once each blue top tube is completely filled, gently invert the sample tube at least five times to ensure complete mixing of the contents.

 

Test Components

Decreasing doses of Ristocen tested for platelet aggregation with pathology review

 

Clinical Indications

Functional platelet aggregation study used to investigate for certain subtypes of von Willebrand disease or platelet function disorder.

Methodology

Platelet aggregation

Additional Information

  • Ten 2.7 mL plastic 3.2% sodium citrate blue top vacutainer tubes per patient. A technologist from the Coagulation Laboratory must be present when the blood is drawn to ensure sample integrity. 
  • Specimens should be drawn with a minimum of trauma or stasis at the venipuncture site and anticoagulated in the ratio of 1 part anticoagulant to 9 parts blood.
  • Once each blue top tube is completely filled, gently invert the sample tube at least five times to ensure complete mixing of the contents.
  • After being drawn , plastic or non-contact surfaced (siliconized) material should be used throughout in order to minimize activation of the platelets during sample preparation.

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

STAT Turnaround Time: N/A

 

Routine Turnaround Time: N/A

 

Testing Schedule: Monday to Friday 8 am to 12 pm. Test must be scheduled.

Synonyms/Keyword Search

Ristocetin induced platelet function studies

Last Review Date

11/11/2024