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Test Code K Potassium

Important Note

Note: For chronic lymphocytic leukemia (CLL) patients with WBC count >100,000, the specimen should be collected in a GOLD SST for potassium analyte.

Specimen and Container/Tube

Specimen Type: Plasma

Preferred Specimen: Li-Heparin Mint Green Top

Other Acceptable specimens: Serum/Gold Top, Serum/Red Top

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent room temperature at 15-25oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

 

Test

Age

Sex

Reference Range

Potassium

All

All

3.5-5.0 mmol/L

Note: Reference range based on in-house studies, recommendations from Tietz Textbook of Clinical Chemistry, and Roche product literature. 

Critical Values

Analyte

Unit

Low

High

Age

Potassium

mmol/L

<2.8

>6.2

>14 days

Potassium

mmol/L

<2.8

>8.0

≤ 14 days

CPT Codes

84132

LOINC Codes

2823-3

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

14 days

Refrigerated

14 days

Frozen

stable

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Test Components

Potassium

Clinical Indications

Potassium, as one of the principal intracellular cations in the body, is a major contributor to tissue osmotic pressure and is the prime determinant of the cell resting membrane potential.

Methodology

Ion Specific Electrode Method (ISE) (Roche Diagnostics)

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • Release of potassium from as few as 0.5 % of the erythrocytes (from specimen collection) can increase the plasma level by 0.5 mmol/L.
  • Hyperkalemia may be seen with anuria or urinary obstruction, tissue damage, violent muscle contraction, adrenal insufficiency, diabetes mellitus, leukemia, hyperparathyroidism, congestive heart failure (less common), metabolic acidosis and heat stroke.
  • Hypokalemia may be seen with prolonged diarrhea or vomiting, diuretic administration, mineralocorticoid excess, familial periodic paralysis, renal tubular acidosis, Bartter’s syndrome, acute intermittent porphyria, congestive heart failure, and Reye’s syndrome.
  • Patients with WBC >100 K/uL and have a diagnosis of chronic lymphocytic leukemia (CLL) have the potential to have falsely elevated potassium when drawn in lithium heparin plasma separator tubes. Therefore patients should be drawn in a  Serum Gold Top or Red Top tube using the order code SSTCP for CMP for chronic lymphocytic leukemia (CPNL FOR CLL PATIENTS ONLY) ,  or SSTKP for BMP for chronic lymphocytic leukemia (KPNL FOR CLL PATIENTS ONLY)  
  • Also included in Basic Metabolic Panel KPNL, Comprehensive Metabolic Panel CPNL, ER Panel I STKG, Renal Function Panel RPNL, and Electrolyte Panel LYTS 

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Last Review Date

8/19/2024