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Test Code IMMFTS Immune Function Test

Important Note

Order Synonym "IMMFTS"

Order Sunquest code "IMMFTS"

Offsite Collection Instructions

“Order must be placed for collection after 4a, received in the laboratory by 5pm.  Monday to Friday ONLY.  Specimen cannot be sent Saturday and Sunday

Turnaround Time

36 – 48 hours from receipt of specimen

Collection Tube

2 to 3 ml whole blood collected in Sodium Heparin (Green top) tube

UCMC Collection Instructions

“Order must be placed for collection after 4a, received in the laboratory by 5pm.  Monday to Friday ONLY.  Specimen cannot be sent Saturday and Sunday.

Reference Values

Interpretation of Results

Low immune response: ATP level ≤225 ng/mL.

Moderate immune response: ATP level 226-524 ng/mL.

Strong immune response: ATP level ≥525 ng/mL.

Results of the ImmuKnow assay should be used in conjunction with clinical presentation, medical history, and other clinical indicators when establishing the immune status of a patient. This is a qualitative assay; therefore, the result does not quantify the level of immunosuppression.

CPT Code

86352

Performing Laboratory

Viracor-IBT Laboratories

1001 NW Technology Drive

Lee's Summit, MO 64086

Methodology

ImmuKnow technology combines cell stimulation, cell selection, and quantification of metabolic markers (ATP) to measure cell-mediated immunity. ImmuKnow measures early response to stimulation by detecting intracellular ATP synthesis in CD4 cells selected from blood by monoclonal antibody-coated magnetic beads. The amount of ATP present in stimulated blood specimens is a measure of lymphocyte activity. Since the CD4 lymphocytes orchestrate cell-mediated immunity responses through immunoregulatory signaling, the measurement of CD4 activation reflects the degree of immune function. This test has been cleared or approved for diagnostic use by the U.S. Food and Drug Administration