Home
HelpTest Code BILN Bilirubin Panel
Specimen and Container/Tube
Specimen Type: Plasma
Preferred Specimen: Li-Heparin Mint Green Top
Other Acceptable specimens: Serum/Red Top, Serum/Gold Top
Specimen Stability
|
Storage Temperature |
Stability |
|
Room temperature |
1 day |
|
Refrigerated |
7 days |
|
Frozen |
6 months |
Collection Instructions
Collect specimen per standard laboratory collection procedures.
Specimen Handling and Transport Instructions
UCMC Onsite Instructions:
- Collect specimen per standard collection procedure and send to laboratory immediately.
UCMC Offsite and UC MedLab Outreach Instructions:
- Samples should be centrifuged within 2 hours of collection.
- Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
- Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
- Samples must be sent room temperature at 15-25oC.
Rejection Criteria
- Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits.
- Specimens that are clotted or grossly hemolyzed.
- Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.
Reference Values
|
Test |
Age |
Sex |
Reference Range |
|
Total Bilirubin |
< 24 Hours |
All |
1.0 - 6.0 mg/dL |
|
Total Bilirubin |
24 - 48 Hours |
All |
2.0 - 8.0 mg/dL |
|
Total Bilirubin |
3 - 5 Days |
All |
4.0 - 12.0 mg/dL |
|
Total Bilirubin |
6 - 14 Days |
All |
0.6 - 7.0 mg/dL |
|
Total Bilirubin |
> 14 Days |
All |
0.1 - 1.0 mg/dL |
|
Test |
Age |
Sex |
Reference Range |
|
Bilirubin, Conjugated |
<14 Days |
All |
0.0 - 0.6 mg/dL |
|
Bilirubin, Conjugated |
>14 Days |
All |
0.0 - 0.3 mg/dL |
|
Test |
Age |
Sex |
Reference Range |
|
Bilirubin, Unconjugated |
<24 hours |
All |
1.0 - 6.0 mg/dL |
|
Bilirubin, Unconjugated |
24 - 48 hours |
All |
2.0 - 8.0 mg/dL |
|
Bilirubin, Unconjugated |
3 - 5 Days |
All |
4.0 - 12.0 mg/dL |
|
Bilirubin, Unconjugated |
6 - 14 Days |
All |
0.6 - 7.0 mg/dL |
|
Bilirubin, Unconjugated |
>14 Days |
All |
0.1 - 1.0 mg/dL |
NOTE: Unconjugated Bilrubin (BU) is a calculation of Total Bilirubin (TBIL) minus the Conjugated Bilirubin (BC).
Critical Values
|
Analyte |
Unit |
Low |
High |
Age |
|
Total Bilirubin |
mg/dL |
N/A |
>18.0 |
0-14 Days |
Turnaround Time
Turnaround times are relative to the time the specimen is received in the test laboratory.
STAT Turnaround Time: 1 hour
Routine Turnaround Time: 4 hours
Testing Schedule: 24/7
Clinical Indications
Measurements of bilirubin are used in the diagnosis of liver disease, in the detection of hemolytic anemia, and to evaluate degrees of jaundice.
Test Components
- Total Bilirubin
- Conjugated Bilirubin
- Calculated Unconjugated Bilirubin
Methodology
- Colormetric Diazo Method (Roche Diagnostics)
- Endpoint Colorimetric (Modified Jendrassik-Grof) (Roche Diagnostics)
CPT Codes
82247, 82248
LOINC Codes
1975-2, 15152-2
Synonyms/Keyword Search
DBIL, BILD, BILC, Direct Bilirubin, NBIL
Additional Information
- Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
- Cyanokit (hydroxocobalamin) at therapeutic concentrations causes significantly lower results. Results from certain multiple myeloma patient samples may show a positive bias in recovery. Not all multiple myeloma patients show the bias and the severity of the bias may vary between patients.
- Grossly hemolyzed specimens inhibit the diazo reaction and falsely low conjugated bilirubin results may be seen.
- Each of these test components may be ordered individually. A test or panel may be ordered only when all components are medically necessary to diagnose or treat an individual patient. If all components are not medically necessary, a less inclusive panel and/or an individual test as appropriate to treat the individual patient should be ordered.
Last Review Date
8/19/2024
Volume
Preferred Volume: 0.5 mL
Minimum Volume: 0.2 mL