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HelpTest Code APOL1B APOL1 Genotyping Assay by Next-Generation Sequencing (NGS), (Blood)
Specimen and Container/Tube
Blood
Rejection Criteria
Inappropriate anticoagulant and >72 hours
Turnaround Time
Not Available
Specimen Type
Blood
Preferred Volume
5 mL
Offsite Collection Instructions
Send within 24 hours or Refrigerate/ send within 72 hours
UCMC Collection Instructions
Send within 72 hours
Test Usage
Qualitative detection of two APOL1 nephropathy risk alleles
(G1
and G2) for African-Americans with a clinical risk or family
history of kidney disease and African-Americans being evaluated
as
living kidney donor.
Critical Results
None
Test Limitations
Other non-G1 and non-G2 variants, copy number alterations,
translocations , and variants in other coding exons or
non-coding
regions that affect gene expression will not be detected.
Test Includes
Detects G1 and G2 nephropathy risk variant in APOL1 exon 6.
Fee Code
376540-31381479
Synonyms
None
STAT Turnaround Time
Not Available
Container/Tube
Lavender top
Specimen Minimum Volume
0.5 mL
Special Instructions
Send within 72 hours
Day(s) Performed
Monday – Friday, 8:00 AM – 4:30 PM
STAT DAY(S) AND TIME(S) PERFORMED
No
CPT
81479
Method Name
Next Generation Sequencing
Reference Values
Interpretative report
Reject Due To
Inappropriate anticoagulant and >72 hours
Pediatric Volume
0.5 mL
Clinical Indications
Qualitative detection of two APOL1 nephropathy risk alleles
(G1
and G2) for African-Americans with a clinical risk or family
history of kidney disease and African-Americans being evaluated
as
living kidney donor.
Transport Instructions
Send within 24 hours or Refrigerate/ send within 72 hours
Test Components
Detects G1 and G2 nephropathy risk variant in APOL1 exon 6.
Methodology
Next Generation Sequencing
Synonyms/Key Search Words
None