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Test Code AMIPK Amikacin, Peak

Specimen and Container/Tube

Specimen Type: Serum

Preferred Specimen: Red Top

Other Acceptable specimens: Serum/Gold Top

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent refrigerated at 2-8oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

Test

Age

Sex

Reference Range

Amikacin

Extended Interval Dosing

All

All

30-80 μg/mL

Amikacin

Conventional Dosing

All

All

15-40 μg/mL

Critical Values

Analyte

Unit

Low

High

Age

Amikacin

μg/mL

N/A

>80.0

All

CPT Codes

80150

LOINC Codes

3319-1

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

8 hours

Refrigerated

2 days

Frozen

4 weeks

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Test Components

Amikacin
 

Clinical Indications

Determination of serum or plasma drug levels is required to achieve optimum therapeutic efficacy and minimize toxicity.

Methodology

Kinetic Interaction of Microparticles in solution (KIMS) (Roche Diagnostics)

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • Determination of serum or plasma drug levels is required to achieve optimum therapeutic efficacy and minimize toxicity.
  • Serum tubes containing separating gel may be used if received in Labortory Services within 2 hours after collection.
  • Collection time varies dependent upon desired measurement of peak or trough values.

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Synonyms/Keyword Search

N/A

Last Review Date

8/14/2024

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