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Mayo Clinic Laboratories

Test Code 1517O PML Assay, t(15;17)Translocation detection (Bone Marrow)

Specimen and Container/Tube

Bone Marrow

Rejection Criteria

>24 hours old, clotted, frozen, anticoagulant other then
EDTA

Turnaround Time

5 Days

Clinical Indications

Used for genetics confirmation of acute promyelocytic
leukemia
or to monitor minimal residual disease

Test Components

Detect 15;17 translocation (PML-RARA) (most common
variants of PML-RARA)

Methodology

RNA based,
Real time PCR

Test Includes

Detect 15;17 translocation (PML-RARA) (most common
variants of PML-RARA)

Specimen Type

Bone Marrow

Preferred Volume

3 mL

Test Usage

Used for genetics confirmation of acute promyelocytic
leukemia
or to monitor minimal residual disease

Fee Code

376555-30081315

Synonyms

APL,
PML-RARA, t(15:17)
translocation

Offsite Collection Instructions

Protect from high or low temperatures. Send within 24 hours.

UCMC Collection Instructions

Send within 24 hours

Test Limitations

May not detect atypical PML-RARA translocations and
other genes or gene partners

STAT Turnaround Time

5 Days

Container/Tube

Lavender top

Specimen Minimum Volume

3 mL

Special Instructions

Send within 24 hours

Day(s) Performed

Monday – Friday, 8:00 AM – 4:30 PM

STAT DAY(S) AND TIME(S) PERFORMED

Yes

CPT

81315

Method Name

RNA based,
Real time PCR

Reference Values

Interpretative report

Reject Due To

>24 hours old, clotted, frozen, anticoagulant other then
EDTA

Pediatric Volume

3 mL

Transport Instructions

Protect from high or low temperatures. Send within 24 hours.

Synonyms/Key Search Words

APL,
PML-RARA, t(15:17)
translocation