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Mayo Clinic Laboratories

Test Code TPO Thyroperoxidase Antibodies, Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  7 days

Reference Values

<9.0 IU/mL

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

CPT Code Information

86376

Report Available

1 to 3 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Method Name

Chemiluminometric Immunoassay

Secondary ID

81765

Testing Algorithm

For more information, see Thyroid Function Ordering Algorithm