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The University of Chicago Medicine Laboratories

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Mayo Clinic Laboratories

Prenatal Cell-Free DNA Screening (MaterniT21)

Important Note

Order LABRFNIPTS in EPIC

Specimen and Container/Tube

Specimen Type:  Whole blood

Preferred Specimen:  Tan-top (Streck) tube (whole blood)

Volume

Preferred Volume: 10 mL whole blood

Minimum Volume: 8 mL whole blood

Specimen Stability

 Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight. 

Collection Instructions

Collect blood according to the standard laboratory collection procedures.

Specimen Handling and Transport Instructions

Maintain specimen at room temperature

Clinical Indications

For pregnancies at increased risk of fetal abnormalities, the MaterniT21 PLUS test delivers a comprehensive NIPT for the analysis of chromosomal regions including trisomies 21, 18, and 13, fetal sex.

Methodology

Cell-free DNA is isolated from the sample and analyzed using massively parallel sequencing technology.

Turnaround Time

3 to 5 days upon receipt at LabCorp

Rejection Criteria

Gestational age less than nine weeks; expired or incorrect blood tubes (including nonglass tubes); quantity not sufficient for analysis; received more than seven days from collections; excessive hemolysis; frozen specimens