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Test Code URPR Urine Protein, Timed

Important Note

If ordering a random collection, use order code RPROT 

Specimen and Container/Tube

Specimen Type: Urine, 24 Hour Timed Collection

Preferred Specimen:  24 Hour Sterile Plastic Container

Other Acceptable specimens: Sterile Clean Glass Container

Specimen Stability

Storage Temperature

Stability

Room temperature

1 day

Refrigerated

7 days

Frozen

1 month

Collection Instructions

  • Provide 24-hour urine collection instructions and container to patient.
  • Collect specimen per standard laboratory collection procedures. 
  • No preservatives or additives.
  • Keep 24 hour urine refrigerated during collection process. 

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

  • Collect specimen per standard collection procedure and send to laboratory immediately.
  • No preservatives or additives.

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection
  • No preservatives or additives
  • Aliquot 10.0 mL of well mixed urine into plastic tube. 
  • Urine samples must then be sent refrigerated at 2-8oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are collected with preservatives or additives.

Reference Values

 

Test

Age

Sex

Reference Range

Urine Protein Timed

All

All

0.05 - 0.10 g/24hr 

Critical Values

Not applicable

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Clinical Indications

Protein measurements in urine may be used in the diagnosis and treatment of disease conditions such as renal or heart diseases, or thyroid disorders, which are characterized by proteinuria or albuminuria.

Test Components

Urine collection duration, Urine total volume, Urine protein random, Urine protein timed 

CPT Codes

84156

LOINC Codes

2889-4

Methodology

Turbidimetric (Benzethonium Chloride) Method (Roche Diagnostics)

Synonyms/Keyword Search

24 hour urine protein

Additional Information

Therapeutic concentrations of Ca-dobesilate, levodopa and phenazopyridine interfere with the assay. Radiopaque media containing organically bound iodine (e.g. Hexabrix) may cause false-high results. The administration of gelatin-based plasma replacements can lead to increased urine protein values. High homogentisic acid concentrations in urine samples lead to false results. Hemoglobin from hemolyzed red cells will interfere with the assay.

Last Review Date

4/7/2025

Volume

Preferred Volume: 10.0 mL

Minimum Volume: 1.0 mL