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HelpTest Code PRLC Prolactin
Specimen and Container/Tube
Serum or Plasma
Rejection Criteria
Whole blood/unspun samples greater than 6 hours will be
rejected.
Turnaround Time
N/A
Test Includes
N/A
Specimen Type
Serum or Plasma
Preferred Volume
0.5 mL
Test Usage
The determination of prolactin is utilized in the diagnosis of anovular cycles, hyperprolactinemic amenorrhea and galactorrhea, gynecomastia and azoo-spermia. Prolactin is also determined when breast cancer and pituitary tumors are suspected.
Critical Results
N/A
Test Limitations
Measured concentration is dependent upon when the blood
sample
was taken, since the secretion of prolactin occurs in episodes
and
is also subject to a 24-hour cycle. The release of prolactin is
promoted physiologically by suckling and stress. Elevated
prolactin
concentrations are caused by a number of pharmaceuticals (e.g.
dibenzodiazepines, phenothiazine), TRH
and estrogen. The release of
prolactin is inhibited by dopamine, L-dopa and ergotamine
derivatives.
Additional Information
There is no high-dose hook effect at prolactin concentrations
up
to 12,690 ng/mL in this assay.
Fee Code
43147
Container/Tube
Preferred: Plain Red Top Tube
Other Acceptable: Li-Heparin, Mint Green Top
Specimen Minimum Volume
0.2 mL
Day(s) Performed
24 hours, 7 days a week including holidays.
STAT DAY(S) AND TIME(S) PERFORMED
N/A
CPT
PRLC: 84146
Method Name
Electrochemiluminescence Immunoassay (ECLIA)
Reference Values
Male: 4.0 �?? 15.2 ng/mL
Female: 4.8 �?? 23.3 ng/mL
Reject Due To
Whole blood/unspun samples greater than 6 hours will be rejected.
STAT Turnaround Time
N/A
Synonyms
N/A
Offsite Collection Instructions
1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated (2 – 8˚C)
UCMC Collection Instructions
1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25˚C)
Included in Additional codes
N/A
Coverage Information
N/A
Stability: Room Temp
N/A
Stability: Refrigerated
14 days
Stability: Frozen
6 months
Pediatric Volume
0.2 mL
Clinical Indications
The determination of prolactin is utilized in the diagnosis
of
anovular cycles, hyperprolactinemic amenorrhea and
galactorrhea,
gynecomastia and azoo-spermia. Prolactin is also determined
when
breast cancer and pituitary tumors are suspected.
Transport Instructions
1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport?�refrigerated?�(2 �?? 8??C)
Test Components
N/A
Specimen Stability
N/A
Methodology
Electrochemiluminescence Immunoassay (ECLIA)
Synonyms/Key Search Words
N/A