Test Code PR3AB Proteinase (PR3) IgG Antibody
Infectious
Specimen and Container/Tube
Specimen Type: Whole blood
Preferred Specimen: Red-top tube
Volume
Preferred Volume: 2 - 3 mL
Minimum Volume: 1 mL
Specimen Stability
|
Storage Temperature |
Stability |
|
Room temperature (20 - 25°C) |
not acceptable |
|
Refrigerated (2 - 8°C) |
7 days |
|
Frozen (-20°C) |
not acceptable |
Collection Instructions
Specimen Collection: Collect blood from venipuncture by aseptic technique.
Specimen Transport: Immediate
Specimen Handling and Transport Instructions
UCMC Onsite Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.
UCMC Offsite and UC MedLab Outreach Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.
Rejection Criteria
- Common specimen rejected situations include: incorrect specimen type, insufficient volume, incorrect collection container, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits.
Reference Values
|
Test |
Age |
Sex |
Reference Range |
|
Negative |
All |
All |
< 1.0 AI |
Turnaround Time
Turnaround times are relative to the time the specimen is received in the test laboratory.
STAT Turnaround Time: not available
Routine Turnaround Time: 2 days
Testing Schedule: Monday - Sunday
Clinical Indications
- Aid in the diagnosis of anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides: Microscopic Polyangiitis (MPA), Necrotising Glomerulonephritis, Churg-Strauss Syndrome, Wegener’s Granulomatosis and the autoimmune renal disorder, Goodpasture’s syndrome
Methodology
Multiplex Flow Immunoassay
CPT Codes
83516
LOINC Codes
74106-6
Synonyms/Keyword Search
PR3, PROTEINASE, ANCA, Autoantibodies to Proteinase 3, ANCA (Antineutrophil Cytoplasmic Antibodies), PR3 (Proteinase 3) Antineutrophil Cytoplasmic Antibodies
Last Review Date
06/09/2026