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Test Code LABCCOKAR CHROMOSOME ANALYSIS (KARYOTYPE), CANCER CYTOGENETICS

Rejection Criteria

Specimens exposed to fixatives

Reference Values

Interpretative Report

CPT Codes

88237, 88239, 88261, 88262, 88264, 88280, 88285

Specimen & Container/Tube

UCMC Onsite Instructions
Bone Marrow/Aspirate/Core: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes

 

UCMC Offsite and UC MedLab Outreach Instructions
Bone Marrow/Aspirate/Core: Please call the Cytogenetics Laboratory (773-702-9153) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Cytogenetics Laboratory (773-702-9153) for custom make collection tubes

Volume

Bone Marrow/Aspirate: >3 mL
Bone Core: >5 mm
Peripheral Blood: >3 mL
CSF & non-CSF Fluid: >3 mL
Lymph Node/Mass: >5 mm

Specimen Handling & Transport Instructions

Transport specimen at room temperature, do not freeze or refrigerate
Specimen should be received by the cytogenetics laboratory <24 hours post collection

For UC MedLab Outreach institutions please contact Pathology Client Services (773-702-8287) for transport instructions

Clinical Indications

Myeloid and lymphoid neoplasms

Test Components

Tissue culture, cell harvesting, slide preparation, GTG banding, chromosome counting and analysis, karyotype

Methodology

Tissue culture and GTG banding

Synonyms/ Search Keyword

Karyotype, G-bands, chromosome analysis

Additional Information

Limitations: Will not detect low level clones, point mutations, or submicroscopic abnormalities

Last Review Date

April 2023