Test Code LABCCOKAR CANCER CYTOGENETICS, CHROMOSOME ANALYSIS

Specimen and Container/Tube

UCMC Onsite Instructions
Bone Marrow/Aspirate/Core: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes

UCMC Offsite and UC MedLab Outreach Instructions
Bone Marrow/Aspirate/Core: Please call the Cytogenetics Laboratory (773-702-6203) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Cytogenetics Laboratory (773-702-6203) for custom make collection tubes

Specimen Stability

Specimens are stable at room temperature up to 24 hours.

Note: Prolonged transport to the laboratory diminishes success of tumor cell viability in culture.

Specimen Handling and Transport Instructions

UCMC Onsite Instructions
Transport specimen at room temperature, do not freeze or refrigerate.

Specimen should be received by the cytogenetics laboratory <24 hours post collection.

Peripheral blood samples can be sent directly to Cytogenetics via tube station #345

UC MedLab Outreach institutions please contact Pathology Client Services (773-702-8287) for transport instructions.

Rejection Criteria

Specimens exposed to fixatives. Specimens collected in EDTA.

Reference Values

Results reported with current recommendations of the International Standing Committee on Human Cytogenomic Nomenclature (ISCN).

Clinical Indications

Myeloid and lymphoid neoplasms

Test Components

Tissue culture
cell harvesting
slide preparation
GTG banding
chromosome counting and analysis
karyotype
interpretive report

CPT Codes

88237
88239
88261
88262
88264
88280
88285

Methodology

GTG banding

Additional Information

Limitations: Will not detect low level clones, point mutations, or submicroscopic abnormalities

Last Review Date

10/9/2024

Specimen & Container/Tube

UCMC Onsite Instructions
Bone Marrow/Aspirate/Core: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes

UCMC Offsite and UC MedLab Outreach Instructions
Bone Marrow/Aspirate/Core: Please call the Cytogenetics Laboratory (773-702-9153) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Cytogenetics Laboratory (773-702-9153) for custom make collection tubes

Volume

Bone Marrow/Aspirate: >3 mL
Bone Core: >5 mm
Peripheral Blood: >3 mL
CSF & non-CSF Fluid: >3 mL
Lymph Node/Mass: >5 mm

Specimen Handling & Transport Instructions

Transport specimen at room temperature, do not freeze or refrigerate
Specimen should be received by the cytogenetics laboratory <24 hours post collection

For UC MedLab Outreach institutions please contact Pathology Client Services (773-702-8287) for transport instructions

Synonyms/ Search Keyword

Karyotype, G-bands, chromosome analysis

Ordering Notes

For questions about Cancer Cytogenetic orders email #UCM-Cytogenetics-Lab, or CytogeneticsLab@uchicagomedicine.org

Turnaround Time

up to 21 days

Please note: Turnaround times can vary based on lab staffing. For urgent needs and requests to expedite testing, please email #UCM-Cytogenetics-Lab, or CytogeneticsLab@uchicagomedicine.org

Synonyms/Key Search Words