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HelpTest Code LABCCMCARRAY SNP CHROMOSOMAL MICROARRAY (SNP-CMA), CANCER CYTOGENETICS
Rejection Criteria
Specimens exposed to fixatives
Reference Values
Interpretative Report
CPT Codes
81277
Specimen & Container/Tube
UCMC Onsite Instructions
Bone Marrow/Aspirate/Core: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Hematopathology Laboratory (x2-1314) for custom made collection tubes
UCMC Offsite and UC MedLab Outreach Instructions
Bone Marrow/Aspirate/Core: Please call the Cytogenetics Laboratory (773-702-9153) for custom made collection tubes
Peripheral Blood: Sodium Heparin (NaHep, dark green top) vacutainer
CSF & non-CSF Fluid: Sterile collection cup or conical tube without additives
Lymph Node/Mass: Please call the Cytogenetics Laboratory (773-702-9153) for custom made collection tubes
Volume
Bone Marrow/Aspirate: >3 mL
Bone Core: >5 mm
Peripheral Blood: >3 mL
CSF & non-CSF Fluid: >3 mL
Lymph Node/Mass: >5 mm
Specimen Handling & Transport Instructions
Transport specimen at room temperature, do not freeze or refrigerate
Specimen should be received by the cytogenetics laboratory <24 hours post collection
For UC MedLab Outreach institutions please contact Pathology Client Services (773-702-8287) for transport instructions
Clinical Indications
Myeloid and lymphoid neoplasms
Test Components
Single nucleotide polymorphism chromosomal microarray (SNP-CMA)
Methodology
This SNP-CMA includes 2.67 million markers for copy number (CN) analysis including approximately 750,000 SNP probes, and 1.9 million non-polymorphic probes for whole genome coverage.
Synonyms/ Search Keyword
microarray, array, SNP array, chromosomal array, CMA
Additional Information
Limitations: Will not detect balanced translocations, low level clones, point mutations, or small insertion/deletions
Last Review Date
April 2023