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The University of Chicago Medicine Laboratories

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Specimen Collection and Handling

Transfusion

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Mayo Clinic Laboratories

Test Code HEINB Heinz Bodies

Specimen and Container/Tube

Specimen Type: Whole blood

Preferred Specimen: lavender top

Other Acceptable specimens: not applicable 

Specimen Stability

Storage Temperature

Stability

Room temperature

(20 - 25°C)

 8 hours 

Refrigerated

(2 - 10°C)

 24 hours 

Frozen

(-20°C)

not acceptable

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

Specimen Handling and Transport Instructions

 

UCMC Onsite Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.

 

UCMC Offsite and UC MedLab Outreach Instructions: Collect specimen per standard collection procedure and send to laboratory immediately. Specimens must be received within 8 hours. If transport is delayed, refrigerate specimens prior to transport. 

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Frozen or heated specimens will be rejected
  • Clotted or quantity not sufficient specimens are not suitable for testing and will be rejected 

 

Reference Values

Analyte

Age

Sex

Reference Range

Heinz 

All

Male and female

Not detected

Critical Values

Not applicable

Clinical Indications

  • Detection of Heinz bodies. Heinz bodies are particles of denatured hemoglobin that are usually attached to the cell membrane
  • Screen for hemolysis due to drugs/toxins, enzyme deficiencies, thalassemias, and unstable hemoglobins.

Test Components

Direct and challenged stain for Heinz bodies

Methodology

Direct stain Crystal Violet, Challenged stain Acetylphenylhydrazine and Crystal Violet Stain

CPT Codes

85441, 85445

LOINC Codes

HEIND 716-1

Additional Information

Not applicable

Volume

Preferred Volume: 4.0 mL

Minimum Volume: 1.0 mL

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: Not available STAT 

 

Routine Turnaround Time: 24 hours

 

Testing Schedule:  Testing is performed daily 8:00 - 2:00 pm ONLY

Synonyms/Search Keywords

Heinz-Ehrlich bodies 

Last Reviewed Date

9/5/2024