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HelpTest Code CRYB Blood Cryptococcocal Antigen
Infectious
Specimen and Container/Tube
Specimen Type: Blood
Preferred Specimen: Red-top Vacutainer
Volume
Preferred Volume: 3 mL
Specimen Stability
|
Storage Temperature |
Stability |
|
Room temperature (20 - 25°C) |
not acceptable |
|
Refrigerated (2 - 10°C) |
24 hours |
|
Frozen (-20°C) |
not acceptable |
Collection Instructions
Specimen Collection: Venipuncture
Specimen Transport: Immediate
Specimen Handling and Transport Instructions
UCMC Onsite Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.
UCMC Offsite and UC MedLab Outreach Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.
Rejection Criteria
- Common specimen rejected situations include: incorrect specimen type, insufficient volume, incorrect collection container, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits.
- Only 1 sample per day will be accepted.
Reference Values
|
Test |
Age |
Sex |
Reference Range |
| Cryptococcus antigen |
All |
All |
Not Detected |
Critical Values
|
Analyte |
Reference Range |
| Cryptococcus antigen |
Positive |
Turnaround Time
Turnaround times are relative to the time the specimen is received in the test laboratory.
STAT Turnaround Time: not available
Routine Turnaround Time: 48 hours
Testing Schedule: Monday - Sunday
Clinical Indications
- Aid in the detection of the capsular polysaccharide antigens of Cryptococcus species complex (Cryptococcus neoformans and Cryptococcus gattii)
- Weakly encapsulated Cryptococcus strains can lead to false negative results.
- False positives can be caused by infections with Trichosporon and Rhodotorula sp.
CPT Codes
86403
LOINC Codes
30186403
Methodology
Lateral flow assay
Synonyms/Keyword Search
FUNGAL, CRYPTOCOCCUS
Last Review Date
01/23/2026