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Mayo Clinic Laboratories

Test Code BUN Blood Urea Nitrogen

Specimen and Container/Tube

Specimen Type: Plasma

Preferred Specimen: Li-Heparin Mint Green Top

Other Acceptable specimens: Serum/Gold Top, Serum/Red Top

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

7 days

Refrigerated

7 days

Frozen

12 months

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent room temperature at 15-25oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

 

Test

Age

Sex

Reference Range

Blood Urea Nitrogen

All

All

7-20 mg/dL

Critical Values

Not applicable 

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Clinical Indications

The determination of urea is the most widely used test for the evaluation of kidney function. The test is frequently used in conjunction with the determination of creatinine for the differential diagnosis of prerenal hyperuremia (cardiac decompensation, water depletion, increased protein catabolism), renal hyperuremia (glomerulonephritis, chronic nephritis, polycystic kidney, nephrosclerosis, tubular necrosis) and postrenal hyperuremia (obstructions of the urinary tract).

Test Components

Blood Urea Nitrogen

Methodology

Spectrophotometric, Kinetic (Roche Diagnostics)

CPT Codes

84540

LOINC Codes

3094-0

Additional Information

Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.

Also included in Basic Metabolic Panel KPNL, Comprehensive Metabolic Panel CPNL, ER Panel I STKG, Renal Function Panel RPNL, CMP for chronic lymphocytic leukemia (CPNL FOR CLL PATIENTS ONLY) SSTCP, BMP for chronic lymphocytic leukemia (KPNL FOR CLL PATIENTS ONLY)  SSTKP

Last Review Date

8/19/2024