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Test Code ALDO Aldolase

Specimen and Container/Tube

Specimen Type: Serum

Preferred Specimen: Red Top

Other Acceptable specimens: Serum/Gold Top, Plasma/Li-Heparin Mint Green Top

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent frozen at -20oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

 

Test

Age

Sex

Reference Range

Aldolase

All

All

2-8 U/L

Critical Values

Analyte

Unit

Low

High

Age

N/A

N/A

N/A

N/A

N/A

CPT Codes

82085

LOINC Codes

1761-6

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

5 hours

Refrigerated

5 days

Frozen

15 days

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Test Components

Aldolase
 

Clinical Indications

Assisting in the detection of muscle disease.

Methodology

Enzymatic Spectrophotometric (Roche Diagnostics)

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • Aldolase values for inactive persons and patients at bed rest are only 50-70% of the values for active individuals. The level at birth is twice as high as in adults; values double in childhood and then slowly fall to the adult range by 18 to 20 years of age.
  • Phenothiazine with high initial values will decrease aldolase value. Other drugs that may increase aldolase level due to muscle damage at the site of injection are corticotropin, quinidine, tetracosactrin, and thiabendazole.

 

Add on requests: 

Refrigerated specimens not removed from the clot for 24 hours result in the aldolase activity being 12% to 46% greater than properly treated specimen.

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: Not available as STAT test

Routine Turnaround Time: Up to 7 days

Testing Schedule: Once per week on Thursday before 12 pm. 

Synonyms/Keyword Search

N/A

Last Review Date

8/19/2024