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Test Code SICK Sickle Hemoglobin Solubility Test

Specimen and Container/Tube

Specimen Type: Whole blood

Preferred Specimen: lavender top

Other Acceptable specimens: not applicable 

Specimen Stability

Storage Temperature

Stability

Room temperature

(20 - 25°C)

8 hours 

Refrigerated

(2 - 10°C)

24 hours 

Frozen

(-20°C)

not acceptable

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

Specimen Handling and Transport Instructions

 

UCMC Onsite Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.

 

UCMC Offsite and UC MedLab Outreach Instructions: Collect specimen per standard collection procedure and send to laboratory immediately. Specimens must be received within 8 hours. If transport is delayed, refrigerate specimens prior to transport. 

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Frozen or heated specimens will be rejected
  • Clotted or quantity not sufficient specimens are not suitable for testing and will be rejected 

 

Reference Values

Analyte

Age

Sex

Reference Range

Sickle 

All

Male and female

Negative

Clinical Indications

  • Qualitative screen for the presence of sickling hemoglobin

Methodology

Hemoglobin solubility

CPT Codes

85660

LOINC Codes

SICK 6864-3

Volume

Preferred Volume: 4.0 mL

Minimum Volume: 1.0 mL

Critical Values

Not applicable

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 60 minutes

 

Routine Turnaround Time: 240 minutes

 

Testing Schedule:  24/7

Test Components

Sickle hemoglobin solubility test

Synonyms/Search Keywords

Sickledex

Additional Information

Qualitative screen only. Does not distinguish between sickle cell disease and sickle cell trait. This test is not recommended as a screen for children <1 year old or in patients with <25% of hemoglobin S.

Last Reviewed Date

9/5/2024