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Test Code SICK Sickle Hemoglobin Solubility Test

Specimen and Container/Tube

Specimen Type: Whole blood

Preferred Specimen: lavender top

Other Acceptable specimens: not applicable 

Specimen Handling and Transport Instructions

 

UCMC Onsite Instructions: Collect specimen per standard collection procedure and send to laboratory immediately.

 

UCMC Offsite and UC MedLab Outreach Instructions: Collect specimen per standard collection procedure and send to laboratory immediately. Specimens must be received within 8 hours. If transport is delayed, refrigerate specimens prior to transport. 

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Frozen or heated specimens will be rejected
  • Clotted or quantity not sufficient specimens are not suitable for testing and will be rejected 

 

Reference Values

Analyte

Age

Sex

Reference Range

Sickle 

All

Male and female

Negative

Critical Values

Not applicable

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 60 minutes

 

Routine Turnaround Time: 240 minutes

 

Testing Schedule:  24/7

CPT Codes

85660

LOINC Codes

SICK 6864-3

Volume

Preferred Volume: 4.0 mL

Minimum Volume: 1.0 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

(20 - 25°C)

 8 hours 

Refrigerated

(2 - 10°C)

 24 hours 

Frozen

(-20°C)

not acceptable

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

Test Components

Sickle hemoglobin solubility test

Clinical Indications

  • Qualitative screen for the presence of sickling hemoglobin

Methodology

Hemoglobin solubility

Synonyms/Search Keywords

Sickledex

Additional Information

Qualitative screen only. Does not distinguish between sickle cell disease and sickle cell trait. This test is not recommended as a screen for children <1 year old or in patients with <25% of hemoglobin S.

Last Reviewed Date

9/5/2024