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The University of Chicago Medicine Laboratories

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Specimen Collection and Handling

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Mayo Clinic Laboratories

Test Code RCRE NEW Urine Creatinine, Random 

Important Note

If ordering a timed collection use order code URCR

Specimen and Container/Tube

Specimen Type: Urine, Random Collection

Preferred Specimen: Sterile Plastic Container

Other Acceptable specimens: Sterile Clean Glass Container

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

  • Collect specimen per standard collection procedure and send to laboratory immediately. 
  • No preservatives or additives.

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection
  • No preservatives or additives
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot urine into plastic tube containing a minimum of 0.2 mL of specimen.
  • Urine samples must then be sent refrigerated at 2-8oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are collected with preservatives or additives.

Reference Values

Test

Age

Sex

Reference Range

Urine Creatinine

All

All

N/A

Critical Values

Not applicable 

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

CPT Codes

82570

LOINC Codes

2161-8

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

3 days

Refrigerated

8 days

Frozen

21 days (not preferred) 

Collection Instructions

  • Collect specimen per standard laboratory collection procedures. 
  • No preservatives or additives.

Test Components

Urine Creatinine

Clinical Indications

The assay of creatinine in urine helps with the diagnosis and treatment of renal disease and renal dialysis. If the Urine Protein/Urine Creatinine ratio is needed please order test code RPRCR. A more sensitive test and better estimation of glomerular filtration rate (GFR) is given by the creatinine clearance test, test code CCLR.

Methodology

Kinetic Colorimetric Assay based on the enzymatic method (Roche Diagnostics)

Synonyms/Keyword Search

Not applicable 

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • Reference ranges for random urine specimens have not been established; subject to ordering physician interpretation only.
  • The presence of ketone bodies can cause artificially high results in urine. High homogentisic acid concentrations in urine samples lead to false results. If preservatives need to be used for other analyte orders, collect sample using Hydrochloric Acid (6N HCl) or Boric Acid (5 g/L).

Last Review Date

4/3/2025