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Test Code PTBG Sex Hormone Binding Globulin (SHBG)

Important Note

This test may be affected by biotin interference. Patients on high dose biotin (5mg/day or more) should not have samples drawn until at least 24 hours after the last biotin administration.

Specimen and Container/Tube

Serum

Rejection Criteria

Whole blood/unspun samples greater than 6 hours will be
rejected.

Turnaround Time

N/A

Test Includes

N/A

Specimen Type

Serum

Preferred Volume

0.5 mL

Test Usage

Measurement of SHBG can be an important indicator of an
excessive/chronic androgenic action where androgen elvels are
normal, but where clinical symptoms would seem to indicate androgen
in excess. SHBG is a useful supplementary parameter in the
determination of androgen where a relatively high concentration of
free androgen (e.g. testosterone) is suspected.

Critical Results

N/A

Fee Code

43218

Container/Tube

Red Top

Specimen Minimum Volume

0.2 mL

Day(s) Performed

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

N/A

CPT

84270

Method Name

Electrochemiluminescence immunoassay (ECLIA)

Reference Values

Prepubertal (1-9 yrs): 28-124 nmol/L
Female (10-40 yrs): 20-100 nmol/L
Male (>10 yrs): 10-80 nmol/L

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

STAT Turnaround Time

N/A

Synonyms

N/A

Test Limitations

N/A

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated (2 – 8˚C)

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25˚C)

Additional Information

N/A

Included in Additional codes

N/A

Coverage Information

N/A

Stability: Room Temp

n/a

Stability: Refrigerated

3 days

Stability: Frozen

1 month

Pediatric Volume

0.2 mL

Clinical Indications

Measurement of SHBG can be an
important indicator of an
excessive/chronic androgenic action where androgen elvels are
normal, but where clinical symptoms would seem to indicate
androgen
in excess. SHBG is a useful supplementary
parameter in the
determination of androgen where a relatively high concentration
of
free androgen (e.g. testosterone) is suspected.

Transport Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport?�refrigerated?�(2 �?? 8??C)

Test Components

N/A

Specimen Stability

n/a

Methodology

Electrochemiluminescence immunoassay (ECLIA)

Synonyms/Key Search Words

N/A