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Test Code NGSCS OncoScreen ST Solid Tumor Panel (Cytology Smear)

Specimen and Container/Tube

Cytology Smear

Rejection Criteria

>72 hours

Turnaround Time

Not Available

Test Includes

Detects hot spot regions of 50 commonly mutated genes in
cancer.
The genes are:ABL1, AKT1, ALK,
APC,
ATM,
BRAF, CDH1,
CDKN2A, CSF1R, CTNNB1,
EGFR, ERB2,
ERBB4, EZH2, FBXW7, FGFR1,
FGFR2, FGFR3, FLT3, GNA11, GNAQ,
GNAS, HNF1A,
HRAS, IDH1,
IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1,
MPL, NOTCH1,
NPM1, NRAS,
PDGFRA,
PIK3CA,
PTEN, PTPN11,
RB1, RET,
SMAD4, SMARCB1, SMO,
SRC, STK11,
TP53, VHL.

Specimen Type

Cytology Smear

Preferred Volume

10 Slides

Fee Code

376540-31081445

Offsite Collection Instructions

Send within 72 hours

Test Usage

Targeted and rapid assay for genomic profiling of solid
tumor
and hematological malignancy specimens to determine appropriate
therapies. It also can be useful for diagnosis, prognosis,
clinical
trials selection and for translational research.

UCMC Collection Instructions

Send within 72 hours

Test Limitations

Will not detect mutations below the analytical sensitivity
of
the assay (5% variant allelic frequency).

Synonyms

None

STAT Turnaround Time

Not Available

Container/Tube

Unstained Cytology Smear Slides

Specimen Minimum Volume

5 Slides

Special Instructions

Send within 72 hours

Day(s) Performed

Monday – Friday, 8:00 AM – 4:30 PM

STAT DAY(S) AND TIME(S) PERFORMED

No

CPT

81445

Method Name

Next Generation Sequencing

Reference Values

Interpretative report

Reject Due To

>72 hours

Pediatric Volume

5 Slides

Clinical Indications

Targeted and rapid assay for genomic profiling of solid
tumor
and hematological malignancy specimens to determine appropriate
therapies. It also can be useful for diagnosis, prognosis,
clinical
trials selection and for translational research.

Transport Instructions

Send within 72 hours

Test Components

Detects hot spot regions of 50 commonly mutated genes in
cancer.
The genes are:ABL1, AKT1, ALK,
APC,
ATM,
BRAF, CDH1,
CDKN2A, CSF1R, CTNNB1,
EGFR, ERB2,
ERBB4, EZH2, FBXW7, FGFR1,
FGFR2, FGFR3, FLT3, GNA11, GNAQ,
GNAS, HNF1A,
HRAS, IDH1,
IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1,
MPL, NOTCH1,
NPM1, NRAS,
PDGFRA,
PIK3CA,
PTEN, PTPN11,
RB1, RET,
SMAD4, SMARCB1, SMO,
SRC, STK11,
TP53, VHL.

Methodology

Next Generation Sequencing

Synonyms/Key Search Words

None