Test Code NGS OncoScreen ST Solid Tumor Panel (Blood)
Specimen and Container/Tube
Blood
Rejection Criteria
Inappropriate anticoagulant and >72 hours
Turnaround Time
Not Available
Test Includes
Detects hot spot regions of 50 commonly mutated genes in
cancer.
The genes are:ABL1, AKT1, ALK,
APC,
ATM,
BRAF, CDH1,
CDKN2A, CSF1R, CTNNB1,
EGFR, ERB2,
ERBB4, EZH2, FBXW7, FGFR1,
FGFR2, FGFR3, FLT3, GNA11, GNAQ,
GNAS, HNF1A,
HRAS, IDH1,
IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1,
MPL, NOTCH1,
NPM1, NRAS,
PDGFRA,
PIK3CA,
PTEN, PTPN11,
RB1, RET,
SMAD4, SMARCB1, SMO,
SRC, STK11,
TP53, VHL.
Specimen Type
Blood
Preferred Volume
3 mL
Fee Code
376540-30181450
Offsite Collection Instructions
Send within 24 hours or Refrigerate/ send within 72 hours
Test Usage
Targeted and rapid assay for genomic profiling of solid
tumor
and hematological malignancy specimens to determine appropriate
therapies. It also can be useful for diagnosis, prognosis,
clinical
trials selection and for translational research.
UCMC Collection Instructions
Send within 72 hours
Test Limitations
Will not detect mutations below the analytical sensitivity
of
the assay (5% variant allelic frequency).
Synonyms
None
STAT Turnaround Time
Not Available
Container/Tube
Lavender top
Specimen Minimum Volume
1 mL
Special Instructions
Send within 72 hours
Day(s) Performed
Monday – Friday, 8:00 AM – 4:30 PM
STAT DAY(S) AND TIME(S) PERFORMED
No
CPT
81450
Method Name
Next Generation Sequencing
Reference Values
Interpretative report
Reject Due To
Inappropriate anticoagulant and >72 hours
Pediatric Volume
1 mL
Clinical Indications
Targeted and rapid assay for genomic profiling of solid
tumor
and hematological malignancy specimens to determine appropriate
therapies. It also can be useful for diagnosis, prognosis,
clinical
trials selection and for translational research.
Transport Instructions
Send within 24 hours or Refrigerate/ send within 72 hours
Test Components
Detects hot spot regions of 50 commonly mutated genes in
cancer.
The genes are:ABL1, AKT1, ALK,
APC,
ATM,
BRAF,
CDH1,
CDKN2A, CSF1R, CTNNB1,
EGFR,
ERB2,
ERBB4, EZH2, FBXW7, FGFR1,
FGFR2, FGFR3, FLT3, GNA11, GNAQ,
GNAS,
HNF1A,
HRAS,
IDH1,
IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1,
MPL,
NOTCH1,
NPM1, NRAS,
PDGFRA,
PIK3CA,
PTEN,
PTPN11,
RB1, RET,
SMAD4, SMARCB1, SMO,
SRC,
STK11,
TP53, VHL.
Methodology
Next Generation Sequencing
Synonyms/Key Search Words
None