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Test Code LIDO Lidocaine

Specimen and Container/Tube

Specimen Type: Serum

Preferred Specimen: Red Top

Other Acceptable specimens: Li Heparin Mint Green Top, Gold Top, Lavendar K2 Top, Lavendar K3 Top

Specimen Handling and Transport Instructions

UCMC Onsite Instructions: 

Collect specimen per standard collection procedure and send to laboratory immediately. 

 

UCMC Offsite and UC MedLab Outreach Instructions: 

  • Samples should be centrifuged within 2 hours of collection.
  • Centrifuge specimens at >2500 x g for 10 minutes at room temperature.
  • Aliquot sample into plastic transport tube containing a minimum of 0.2 mL of specimen.
  • Samples must be sent refrigerated at 2-8oC.

Rejection Criteria

  • Common specimen rejected situations include: incorrect specimen type, insufficient volume, missing or incomplete specimen identifiers, incorrect specimen transport, or specimens outside stability limits. 
  • Specimens that are clotted or grossly hemolyzed.
  • Specimens that were transported unspun/whole blood and draw time is greater than 6 hours.

Reference Values

Test

Age

Sex

Reference Range

Lidocaine

N/A

N/A

2.0 - 5.0 μg/mL

Critical Values

Analyte

Unit

Low

High

Age

Lidocaine

μg/mL

N/A

> 9.0

All

CPT Codes

80176

LOINC Codes

3714-3

Volume

Preferred Volume: 0.5 mL

Minimum Volume: 0.2 mL

Specimen Stability

Storage Temperature

Stability

Room temperature

8 hours

Refrigerated

7 days

Frozen

 N/A

Collection Instructions

Collect specimen per standard laboratory collection procedures. 

 

Test Components

Lidocaine
 

Clinical Indications

Quantitative determination of lidocaine in serum.

Methodology

Enzyme-Multiplied Immunoassay Technique (EMIT) (Siemens Healthcare Diagnostics)

Additional Information

  • Results should always be assessed in conjunction with patient's medical history, clinical examination and other findings.
  • The factors that can influence the relationship between lidocaine serum or plasma concentrations and clinical response include the severity and type of arrhythmia and heart disease, liver function, kidney function, circulatory function, age, general state of health, diet, smoking, and use of other drugs.
  • The concentration of lidocaine in serum or plasma depends on the time of the last drug dose; dosage form; mode of administration; concomitant drug therapy; sample condition; time of sample collection; and individual variations in absorption, biotransformation, distribution, and excretion. These parameters must be considered when interpreting results.
  • Recommendations include draw specimens 12 hours after initiating therapy for arrhythmia prophylaxis, then every 24 hours thereafter.

Turnaround Time

Turnaround times are relative to the time the specimen is received in the test laboratory. 

 

STAT Turnaround Time: 1 hour

Routine Turnaround Time: 4 hours

Testing Schedule: 24/7

Synonyms/Keyword Search

N/A

Last Review Date

02/10/23