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Test Code CRY NEW Cryoglobulin, Semiquantitative

Specimen and Container/Tube

Blood

Red top on warm pack

Specimen Handling and Transport Instructions

  • Collect 10mL of blood in Red Top tube.Transport blood specimen on warm pack to processing area of lab.
  • Allow blood to clot at 37°C, typically 15-30 minutes. Use a 37°C water bath or 37°C incubator if available, or keep the blood on warm packs if that is the only option.Promptly centrifuge the blood after clotted at room temperature for 5 minutes at 5,500 rcf (Calculate rpm depending on centrifuge rotor size). (Do NOT centrifuge at 4°C)
  • Remove all serum into a clean aliquot tube.Transfer serum at room temperature to UCMC Clinical Immunology Laboratory.It would be helpful to notify the Clinical Immunology Lab that a sample is being sent to ensure it is placed at 37°C upon arrival.

Rejection Criteria

Whole blood/unspun samples greater than 6 hours will be
rejected.

Reference Values

Negative <0.5%

Turnaround Time

Day(s) Performed

Monday through Sunday

CPT Codes

82595

LOINC Codes

30182595

Volume

Minimum Volume 7ml

Perferred Volume 10 ml

Pediatric Volume   7 mL

Collection Instructions

Offsite

  • Collect 10mL of blood in Red Top tube.Transport blood specimen on warm pack to processing area of lab.Allow blood to clot at 37°C, typically 15-30 minutes. Use a 37°C water bath or 37°C incubator if available, or keep the blood on warm packs if that is the only option.Promptly centrifuge the blood after clotted at room temperature for 5 minutes at 5,500 rcf (Calculate rpm depending on centrifuge rotor size). (Do NOT cetnrifuge at 4°C) Remove all serum into a clean aliquot tube.Transfer serum at room temperature to UCMC Clinical Immunology Laboratory.It would be helpful to notify the Clinical Immunology Lab that a sample is being sent to ensure it is placed at 37°C upon arrival.

Methodology

Precipitation

Last Reviewed Date

8/24/23

Additional Information

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