Test Code CPRION CSF Prion Disease (RTQulC, Tau, 14 3 3) NOT FOR ALZHEIMER ?�

Important Note

Epic orderable code: LABRFCPRION

Specimen and Container/Tube

Cerebrospinal Fluid

Rejection Criteria

Bloody collection

Turnaround Time

Not available as a STAT order

Specimen Type

Cerebrospinal Fluid

Preferred Volume

2 to 5ml

Collection Instructions

Collect CSF by lumbar puncture. Discard the first 2 ml of CSF that flows from the tap. Collect 2-5 ml of clear, colorless CSF

for testing. Bloody CSF cannot be accurately tested. A minimum of 2.0ml is required for testing. Freeze CSF immediately

after collection. Store CSF at -80°C (or at least -20°C) until shipping the specimen on dry ice.

Reference Values

RT-QuIC =?� Negative

T-tau Protein = 0 to 1149 pg/ml

14-3-3 = Negative

Availability

Specimen must be received in the laboratory Monday through Thursday ONLY.

Specimens cannot be sent out on Friday, Saturday or Sunday.

CPT

86317,84182,87798

Reject Due To

Bloody collection

Method Name

ELISA (enzyme-linked immunosorbent assay)

STAT Turnaround Time

Not available as a STAT order

Test Includes

RT-QuIC

T-tau protein

14-3-3

Performing Laboratory

National Prion Disease Pathology Surveillance Center

NPDPSC Institute of Pathology, CWRU

Cleveland, Ohio 44106-4907

Test Components