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Mayo Clinic Laboratories

Test Code CGFPOC FISH, products of conception

Important Note

Chorionic villi preferred

Specimen and Container/Tube

Products of conception (Chorionic villi) or other fetal tissues collected in a sterile specimen cup w/ transport media (provided by the lab) or sterile saline.

Rejection Criteria

Formalin fixed tissue cannot be processed by the laboratory; Non-pregnancy tissue (at the discretion of the section director or supervisor)

Reference Values

Interperative Report

Critical Values

N/A

Turnaround Time

N/A

CPT Codes

88271 x 5;  

88275

LOINC Codes

N/A

Volume

Preferred:  10-25mg of villi                

Amount needed by test:                    BU Culture: 5-15mg of villi                AneuVysion:  5-10mg of villi

Collection Instructions

Specimen should be collected in a sterile specimen cup with transport media (provided by the lab) or sterile saline.  Refrigerate at 4°C and deliver to laboratory within 24 hours of specimen collection.  

Synonyms/ Search Keyword

FISH

Additional Information

Test Limitations:  AneuVysion does not detect structural chromosome abnormalities, mosaicism, and numerical abnormalities of other chromosomes.

Last Review Date

12/16/2022

Specimen Stability

Refrigerate at 4°C and deliver to laboratory within 24 hours of specimen collection.  

Clinical Indications

AneuVysion is indicated for the rapid diagnosis of aneuploidy for chromosomes 13, 18, 21, X and Y.

Specimen Handling & Transport Instructions

Refrigerate at 4°C and deliver to laboratory within 24 hours of specimen collection.  POC speimen can be tubed to J-601  (Tube station #461)

Test Components

AneuVysion FISH (includes probes for chromsomes 13, 18, 21, X, Y)

Methodology

Dual or tri-color fluorescent DNA probes with DAPI counterstain