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HelpTest Code VALP Valproic Acid in Serum
Specimen Type
Serum
Container
Red top
Preferred Volume
5 mL
UCMC Collection Instructions
Peak level: 30 min after completion of
dose
Trough level: 30 min before next dose
Availability
24/7
Turnaround Time
4 hours
STAT Availability
Available
Test Usage
Useful for monitoring therapy, assessing compliance and evaluating potential toxicity
Test Methodology
Homogeneous Enzyme Immunoassay Technique (EMIT)
CPT Code
80164
STAT Turnaround Time
1 hour
Minimum Volume
1 mL
Reference Range
therapeutic range: 50 – 100 µg/mL
Critical Results
>200 µg/mL
Test Limitations
Co-administration of other anti-epileptic drugs can
significantly affect valproic acid metabolism.
Several factors complicate interpretation of valproic
acid levels, including time interval between drug
administration and blood sampling, the type of seizures treated,
albumin concentration and factors affecting albumin binding of
valproic acid , and the presence of other anti-epileptic drugs and
pharmacologically-active metabolites of valproic acid
Test Includes
Quantitative determination of valproic acid in human serum
Fee Code
43683
Synonyms
depakote