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HelpTest Code METAR Metanephrines, Fractionated, Random, Urine
Reporting Name
Metanephrines, Fract., Random, UUseful For
A second-order screening test for the presumptive diagnosis of pheochromocytoma in patients with nonepisodic hypertension
Confirming positive plasma metanephrine results in patients with nonepisodic hypertension
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| RCTU | Creatinine Conc | No | Yes |
| METAU | Metanephrines, Fractionated, U | No | Yes |
Performing Laboratory
Mayo Medical Laboratories in Rochester
Specimen Type
UrineSpecimen Required
Supplies: Urine Tubes, 10 mL (T068)
Patient Preparation: Tricyclic antidepressants and labetalol and sotalol (beta blockers) may elevate levels of metanephrines. If clinically feasible, these medications should be discontinued at least 1 week before collection.
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic urine tube (T068)
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Frozen (preferred) | 14 days |
| Ambient | 7 days | |
| Refrigerated | 7 days |
Reference Values
METANEPHRINE/CREATININE
Normotensives
0-2 years: 82-418 mcg/g creatinine
3-8 years: 65-332 mcg/g creatinine
9-12 years: 41-209 mcg/g creatinine
13-17 years: 30-154 mcg/g creatinine
≥18 years: 29-158 mcg/g creatinine
NORMETANEPHRINE/CREATININE
Males
Normotensives
0-2 years: 121-946 mcg/g creatinine
3-8 years: 92-718 mcg/g creatinine
9-12 years: 53-413 mcg/g creatinine
13-17 years: 37-286 mcg/g creatinine
18-29 years: 53-190 mcg/g creatinine
30-39 years: 60-216 mcg/g creatinine
40-49 years: 69-247 mcg/g creatinine
50-59 years: 78-282 mcg/g creatinine
60-69 years: 89-322 mcg/g creatinine
≥70 years: 102-367 mcg/g creatinine
Females
Normotensives
0-2 years: 121-946 mcg/g creatinine
3-8 years: 92-718 mcg/g creatinine
9-12 years: 53-413 mcg/g creatinine
13-17 years: 37-286 mcg/g creatinine
18-29 years: 81-330 mcg/g creatinine
30-39 years: 93-379 mcg/g creatinine
40-49 years: 107-436 mcg/g creatinine
50-59 years: 122-500 mcg/g creatinine
60-69 years: 141-574 mcg/g creatinine
≥70 years: 161-659 mcg/g creatinine
TOTAL METANEPHRINE/CREATININE
Males
Normotensives
0-2 years: 241-1,272 mcg/g creatinine
3-8 years: 186-980 mcg/g creatinine
9-12 years: 110-582 mcg/g creatinine
13-17 years: 78-412 mcg/g creatinine
18-29 years: 96-286 mcg/g creatinine
30-39 years: 106-316 mcg/g creatinine
40-49 years: 117-349 mcg/g creatinine
50-59 years: 130-386 mcg/g creatinine
60-69 years: 143-427 mcg/g creatinine
≥70 years: 159-472 mcg/g creatinine
Females
Normotensives
0-2 years: 241-1,272 mcg/g creatinine
3-8 years: 186-980 mcg/g creatinine
9-12 years: 110-582 mcg/g creatinine
13-17 years: 78-412 mcg/g creatinine
18-29 years: 131-467 mcg/g creatinine
30-39 years: 147-523 mcg/g creatinine
40-49 years: 164-585 mcg/g creatinine
50-59 years: 184-655 mcg/g creatinine
60-69 years: 206-733 mcg/g creatinine
≥70 years: 230-821 mcg/g creatinine
Day(s) and Time(s) Performed
Monday through Friday; 4 p.m.
Test Classification
This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83835
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| METAR | Metanephrines, Fract., Random, U | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 21546 | Metanephrine/Creatinine | 35644-4 |
| RCTU | Creatinine Conc | 2161-8 |
| 21547 | Normetanephrine/Creatinine | 44342-4 |
| 21548 | Total Metanephrine/Creatinine | 32655-3 |
Reject Due To
|
Hemolysis |
NA |
|
Lipemia |
NA |
|
Icterus |
NA |
|
Other |
NA |
Method Name
RCTU: Enzymatic Colorimetric Assay
METAU: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request Form (T729) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/oncology-request-form.pdf)