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Test Code LIDO Lidocaine

Specimen Type

Serum

Container/Tube

Red Top

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated  (2 – 8C).

Turnaround Time

4 hours

Test Includes

N/A

Preferred Volume

0.5 mL

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25C).

Critical Results

>9 µg/mL

Test Limitations

The factors that can influence the relationship between
lidocaine serum or plasma concentrations and clinical response
include the severity and type of arrhythmia and heart disease,
liver function, kidney function, circulatory function, age, general
state of health, diet, smoking, and use of other drugs.

The concentration of lidocaine in serum or plasma depends on the
time of the last drug dose; dosage form; mode of administration;
concomitant drug therapy; sample condition; time of sample
collection; and individual variations in absorption,
biotransformation, distribution, and excretion. These parameters
must be considered when interpreting results.

Fee Code

43667

Specimen Minimum Volume

0.2 mL

DAY(S) AND TIME(S) PERFORMED

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

Available

CPT

80176

Method Name

Homogeneous Enzyme Immunoassay Technique (EMIT)

Reference Values

Therapeutic range:
Adults:            


1.5 – 6.0 µg/mL 

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

STAT Turnaround Time

1 hour

Synonyms

N/A

Test Usage

Quantitative determination of lidocaine in serum.

Additional Information

Pharmacokinetic factors influence the correct time of sample
collection after the last drug dose. These factors include dosage
form, mode of administration, concomitant drug therapy, and
biological variations affecting drug disposition.

Recommendations include draw specimens 12 hours after initiating
therapy for arrhythmia prophylaxis, then every 24 hours
thereafter.

Included in Additional codes

N/A

Coverage Information

N/A

Stability: Room Temp

1 day

Stability: Refrigerated

7 days

Stability: Frozen

Stable