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Test Code LAAPS2 LA/APS Level 2 Antigenic Package

Specimen Type

Serum

Container/Tube

1 Red top tube

Offsite Collection Instructions

Whole blood or serum samples might be sent to the
laboratory.

Centrifugation instructions:

  • Serum specimen should be centrifuged at >2500 x g
    for 10 minutes.
  • Aliquot removed serum into 2 tubes containing minimum of
    0.5 mL of specimen each. They may be sent refrigerated or frozen.

Note: Frozen samples that have thawed in transit
will be rejected.

Turnaround Time

7 days

Test Includes

The package includes antigenic testing for IgA antibodies
directed against beta-2 GPI and against
cardiolipin. It additionally includes antigenic testing for
IgG and IgM antibodies directed
against phosphatidylserine/prothrombin complexes.

Preferred Volume

2 mL

UCMC Collection Instructions

Specimens for level 2 antigenic testing can be collected and
sent to the lab at any time.

Test Usage

The package includes antigenic testing for detection of
antiphospholipid antibodies.

Fee Code

30286147, 30286146, 30386148, 30486148

Synonyms

Lupus; LA; APS; LA/APS; APS/LA, Level 2;
Anticardiolipin IgA Antibodies; Beta-2 Glycoprotein I IgA
Antibodies; Antiphosphatidylserine/prothrombin Antibodies;
LAAPS2

STAT Turnaround Time

n/a

Specimen Minimum Volume

1 mL

DAY(S) AND TIME(S) PERFORMED

Testing will be performed on Wednesday of each week. Samples
to be tested should be in the lab no later than 8:30 am on
Wednesday in order to be included in that run

STAT DAY(S) AND TIME(S) PERFORMED

Not Available

CPT

86147, 86146, 86148

Method Name

ELISA

Reference Values

Anticardiolipin IgA:

Negative: <12.0 APL

Borderline positive: 12.0-19 APL
Medium positive: 20-80 APL

High positive: >80 APL
 

Beta-2 GPI IgA: <20.1 U/mL
 

APS/PT IgG: <30.1 U/mL
 

APS/PT IgM: <30.1 U/mL

Reject Due To

Specimens grossly hemolyzed