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Test Code IGM Immunoglobulin M

Specimen Type

Plasma

Container/Tube

Li-Heparin  Mint Green Top

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated  (2 – 8C).

Turnaround Time

4 hours

Test Includes

N/A

Preferred Volume

0.5 mL

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25C).

Critical Results

N/A

Test Limitations

It is known that the so-called paraproteins secreted in
monoclonal gammopathies (monoclonal immunoglobulinemia) may differ
from the respective immunoglobulins of polyclonal origin by amino
acid composition and size. This may impair the binding to antibody
and hence impair accurate quantitation.

Fee Code

43057

Synonyms

N/A

Specimen Minimum Volume

0.2 mL

DAY(S) AND TIME(S) PERFORMED

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

N/A

CPT

82784

Method Name

Immunoturbidimetric Assay

Reference Values

Age      Value (mg/dL)

> 14Y   50-320
12         70-150
11         66-155
10         80-150
9          
55-160
8          
68-175
7          
60-175
6          
55-210
5          
40-180
4          
52-200
3          
46-190
2          
72-160
7M        36-104
4M        25-120
1M        12-87
0          
11-35

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

STAT Turnaround Time

N/A

Test Usage

Increased polyclonal IgM levels are found in viral, bacterial,
and parasitic infections, liver diseases, rheumatoid arthritis,
scleroderma, cystic fibrosis and heroin addiction. Monoclonal IgM
is increased in Waldenström’s macroglobulinemia.
Increased loss of IgM is found in protein-losing enteropathies and
in burns.

Decreased synthesis of IgM occurs in congenital and acquired
immunodeficiency syndromes.

Additional Information

Once per admit.  
If monitoring an identified paraprotein, then once per week.

Stability: Room Temp

2 months

Stability: Refrigerated

4 months

Stability: Frozen

6 months