Test Code IGG Immunoglobulin G (IgG)
Specimen Type
Plasma
Container/Tube
Li-Heparin Mint Green Top
Offsite Collection Instructions
1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated (2 – 8C).
Turnaround Time
4 hours
Test Includes
N/A
Preferred Volume
0.5 mL
UCMC Collection Instructions
1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25C).
Critical Results
N/A
Test Limitations
It is known that the so-called paraproteins secreted
inmonoclonal gammopathies (monoclonal immunoglobulinemia) may
differ from the respective immunoglobulins of polyclonal origin
by
amino acid composition and size. This may impair the binding to
antibody and hence impair accurate quantitation.
Fee Code
43056
Synonyms
N/A
Specimen Minimum Volume
0.2 mL
DAY(S) AND TIME(S) PERFORMED
24 hours, 7 days a week including holidays.
STAT DAY(S) AND TIME(S) PERFORMED
N/A
CPT
82784
Method Name
Immunoturbidimetric Assay
Reference Values
Age Value (mg/dL)
> 14Y 800-1700
12 770-1510
11 850-1300
10 730-1350
9
760-1330
8
730-1410
7 570-1320
6
650-1410
5 640-1420
4
540-1440
3 500-1360
2
520-1080
7M 350-1180
4M 190-860
0
750-1500
Reject Due To
Whole blood/unspun samples greater than 6 hours will be
rejected.
STAT Turnaround Time
N/A
Test Usage
Polyclonal IgG increases in serum/plasma may be present in
systemic lupus erythematosis, chronic liver diseases
(infectious
hepatitis and Laennec’s cirrhosis), infectious diseases
and
cystic fibrosis. Monoclonal IgG increases in IgG?myeloma.
Decreased synthesis of IgG is found in congenital and
acquired
immunodeficiency diseases and selective IgG subclass
deficiencies,
such s Bruton type agammaglobulinemia. Decreased IgG
concentrations
in serum and plasma are seen in protein-losing enteropathies,
nephrotic syndrome and through the skin from burns. Increased
IgG
metabolism is found in Wiskott-Aldrich syndrome, myotonic
dystrophy
and with anti-immunoglobulin antibodies.
Additional Information
Once per admit.
If monitoring an identified paraprotein, then once per week.
Included in Additional codes
N/A
Coverage Information
N/A
Stability: Room Temp
4 months
Stability: Refrigerated
8 months
Stability: Frozen
8 months