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Test Code IGG Immunoglobulin G (IgG)

Specimen Type

Plasma

Container/Tube

Li-Heparin  Mint Green Top

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated  (2 – 8C).

Turnaround Time

N/A

Test Includes

N/A

Preferred Volume

0.5 mL

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25C).

Critical Results

N/A

Test Limitations

It is known that the so-called paraproteins secreted
inmonoclonal gammopathies (monoclonal immunoglobulinemia) may
differ from the respective immunoglobulins of polyclonal origin
by
amino acid composition and size. This may impair the binding to
antibody and hence impair accurate quantitation.

Fee Code

43056

Synonyms

N/A

Specimen Minimum Volume

0.2 mL

Day(s) Performed

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

N/A

CPT

82784

Method Name

Immunoturbidimetric Assay

Reference Values

Age?�?�?�?�?� Value (mg/dL)

> 14Y?�?� 800-1700
12?�?�?�?�?�?�?� 770-1510
11?�?�?�?�?�?�?� 850-1300
10?�?�?�?�?� ?� 730-1350
9?�?�?�?�?�?�?�?�?�
760-1330
8?�?�?�?�?�?�?�?�?�
730-1410
7?�?�?�?�?�?� ?�?� 570-1320
6?�?�?�?�?�?�?�?�?�
650-1410
5?�?�?�?�?�?� ?�?� 640-1420
4?�?�?�?�?�?�?�?�
?�540-1440
3?�?�?�?�?�?�?� ?� 500-1360
2?�?�?�?�?�?�?�?�
?�520-1080
7M?�?�?� ?� ?�350-1180
4M?�?�?�?�?�?� 190-860
0?�?�?�?�?�?�?�?�?�
750-1500

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

STAT Turnaround Time

N/A

Test Usage

Polyclonal IgG increases in serum/plasma may be present in
systemic lupus erythematosis, chronic liver diseases (infectious
hepatitis and Laennec’s cirrhosis), infectious diseases and
cystic fibrosis. Monoclonal IgG increases in IgG?myeloma.

Decreased synthesis of IgG is found in congenital and acquired
immunodeficiency diseases and selective IgG subclass deficiencies,
such s Bruton type agammaglobulinemia. Decreased IgG concentrations
in serum and plasma are seen in protein-losing enteropathies,
nephrotic syndrome and through the skin from burns. Increased IgG
metabolism is found in Wiskott-Aldrich syndrome, myotonic dystrophy
and with anti-immunoglobulin antibodies.

Additional Information

Once per admit. ?�
If monitoring an identified paraprotein, then once per week.

Included in Additional codes

N/A

Coverage Information

N/A

Stability: Room Temp

4 months

Stability: Refrigerated

8 months

Stability: Frozen

8 months

Specimen and Container/Tube

Plasma

Pediatric Volume

0.2 mL

Clinical Indications

Polyclonal IgG increases in serum/plasma may be present in
systemic lupus erythematosis, chronic liver diseases
(infectious
hepatitis and Laennec�??s cirrhosis), infectious diseases
and
cystic fibrosis. Monoclonal IgG increases in IgG?myeloma.

Decreased synthesis of IgG is found in congenital and
acquired
immunodeficiency diseases and selective IgG subclass
deficiencies,
such s Bruton type agammaglobulinemia. Decreased IgG
concentrations
in serum and plasma are seen in protein-losing enteropathies,
nephrotic syndrome and through the skin from burns. Increased
IgG
metabolism is found in Wiskott-Aldrich syndrome, myotonic
dystrophy
and with anti-immunoglobulin antibodies.

Transport Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport?�refrigerated?�?�(2 �?? 8C).

Test Components

N/A

Specimen Stability

4 months

Rejection Criteria

Whole blood/unspun samples greater than 6 hours will be
rejected.

Methodology

Immunoturbidimetric Assay

Synonyms/Key Search Words

N/A