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Test Code IGA Immunoglobulin A (IgA)

Specimen Type

Plasma

Container/Tube

Li-Heparin  Mint Green Top

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be spun and
aliquoted
3. Transport refrigerated  (2 – 8C).

Turnaround Time

4 hours

Test Includes

N/A

Preferred Volume

0.5 mL

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Within 2 hours of collection the sample must be received in
Laboratory Service Center
3. Transport room temperature (15 – 25C).

Critical Results

N/A

Test Limitations

It is known that the so-called paraproteins secreted inIt is
known that the so-called paraproteins secreted in monoclonal
gammopathies (monoclonal immunoglobulinemia) may differ from the
respective immunoglobulins of polyclonal origin by amino acid
composition and size. This may impair the binding to antibody and
hence impair accurate quantitation.

Fee Code

43055

Synonyms

N/A

Specimen Minimum Volume

0.2 mL

DAY(S) AND TIME(S) PERFORMED

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

N/A

CPT

82784

Method Name

Immunoturbidimetric Assay

Reference Values

Age Value (mg/dL)

> 14Y 100-490
12       100-325
11         91-225
10         70-222
9         108-200
8          74-260
7          65-240
6          83-217
5          52-220
4          52-210
3          45-135
2          36-165
7M      36-165
4M      10-96
1M        6-58
0        < 6

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

STAT Turnaround Time

N/A

Test Usage

Increased polyclonal IgA levels may occur in chronic liver
diseases, chronic infections, autoimmune disorders (rheumatoid
arthritis, systemic lupus erythematosis), sarcoidosis and
Wiscott?Aldrich syndrome. Monoclonal IgA increases in IgA
myeloma.

Decreased synthesis of IgA is observed in acquired and
congenital immunodeficiency diseases such as Bruton type
agammaglobulinemia. Reduced levels of IgA can be caused by
protein-losing gastroenteropathies and loss through skin from
burns.

Additional Information

Once per admit.  
If monitoring an identified paraprotein, then once per week.

Included in Additional codes

N/A

Coverage Information

N/A

Stability: Room Temp

8 months

Stability: Refrigerated

8 months

Stability: Frozen

8 months