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Test Code DICSCR DIC Panel

Specimen Type

Plasma/Whole Blood


One light blue top tube (3.2% sodium citrate) and
one lavender top tube

Offsite Collection Instructions

Whole blood sample must arrive in the laboratory within
three hours of specimen collection.


If transport time exceeds three hours, follow centrifugation

  • Samples must be centrifuged at >2500 x g for 10 minutes
    at room temperature.
  • Carefully remove the plasma from the cells using a plastic
    transfer pipette avoiding the buffy coat.
  • Aliquot removed plasma into 2 plastic tubes containing a
    minimum of 500 uL of specimen in each tube.
  • The plasma samples must then be frozen at -20ºC.
  • Once solidly frozen, they must be shipped on dry ice.
    Samples that have thawed in transit will be rejected.

Note: For clients who do not have access to dry ice DO
NOT freeze the specimen. Follow the centrifugation instructions and
send fresh plasma or send whole blood sample. It now becomes
vital that the specimen arrives in the lab within three hours of


Do not centrifuge lavender tube
for Platelet Count. Do Not Freeze.

Turnaround Time

4 hours

Test Includes

D Dimer, PT, FIBB, Platelet Count and
DIC Score

Preferred Volume

1 mL plasma and 2 mL blood in 4 mL lavender tube

STAT Turnaround Time

1 hour

Critical Results

INR >3.9

Fibrinogen <80mg/dL,
Platelet Count <30 or >1,000 (x 10³/µL) when patient has not had
similar values within past 48 hours.
All platelet counts < 10 (x 10³/µL).

Additional Information

All 3.2% sodium citrate light blue top tubes require a ratio
of 9 parts blood to 1 part anticoagulant (example: a 3.0 mL tube
requires 2.7 mL blood added to 0.3 mL of anticoagulant).
 Risk assessment:

Does the patient have an underlying disorder
known to be associated with overt DIC?

If yes, proceed
If not, do not use this algorithm

 Order global coagulation tests (Platelet Count,
D-Dimer, PT, Fibrinogen)

 Score the test results:

Platelet Count (per uL): >100,000 = 0;
50,000-100,000 = 1; <50,000 = 2

Elevated D-Dimer (ug/mL FEU):


0.4-4.0 = 2,

>4.0 = 3

Prolongation (in seconds) of PT above
upper limit of its normal reference range:

<3.0 = 0,
3.0-6.0 = 1,

>6.0 = 2

Fibrinogen level (mg/dL):

>100 = 0
<100 = 1

Calculate score:

If score 5 or greater, compatible with
overt DIC: Repeat score daily

If score less than 5, suggestive (not
affirmative) for non-overt DIC:
Repeat next 1-2 days

Fee Code

D-dimer: 30585379

Fibrinogen: 30585384

PT: 30585610

Platelet Count: 53449

Test Usage

Contains PT/INR, platelet count,
fibrinogen, and D-dimer. Used
to score patient’s likelihood of DIC by laboratory

Specimen Minimum Volume

0.5 mL plasma and 2 mL blood in 4 mL lavender tube






D-dimer: 85379

Fibrinogen: 85384

PT: 85610

Platelet Count: 85049

Method Name

Clotting, Latex Immunoassay, and Sysmex XE5000 (plate count)

Reference Values

See individual tests

Reject Due To

Whole blood/unspun samples greater than 6 hours will be