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Test Code DGXN Digoxin

Specimen Type

Serum

Container/Tube

Red Top

Offsite Collection Instructions

1. Collect sample following standard collection methods
2. Recommended that digoxin serum levels should be drawn at least
4
hours after an intravenous dose and at least 6 hours after an
oral
dose (optimally 12-24 hours after a dose).
3. Within 2 hours of collection the sample must be spun and
aliquoted
4. Transport refrigerated  (2 – 8C).

Turnaround Time

4 hours

Test Includes

N/A

Preferred Volume

0.5 mL

UCMC Collection Instructions

1. Collect sample following standard collection methods
2. Recommended that digoxin serum levels should be drawn at least
4
hours after an intravenous dose and at least 6 hours after an
oral
dose (optimally 12-24 hours after a dose).
3. Within 2 hours of collection the sample must be received in
Laboratory Service Center
4. Transport room temperature (15 – 25C).

STAT Turnaround Time

1 hour

Test Usage

Measurements are used in the diagnosis and treatment of digoxin
overdose and in monitoring levels of digoxin to ensure proper
therapy.

Critical Results

N/A

Test Limitations

Endogenous substances such as DLIF
(digoxin-like immunoreactive factors) may interfere with this assay
by yielding slightly elevated results.

The manufacturer of Digoxin Immune FAb (Antibody fragment
therapy) has stated that no immunoassay technique is suitable for
quantitating digoxin in serum from patients undergoing this
treatment.

Falsely elevated digoxin values are obtained in patients
undergoing digitoxin therapy. Samples from patients using Uzara for
treatment of diarrhea may cause falsely elevated digoxin
results.

Coverage Information

N/A

Fee Code

43695

Stability: Room Temp

n/a

Stability: Refrigerated

24 hours

Stability: Frozen

1-2 weeks

Specimen Minimum Volume

0.2 mL

DAY(S) AND TIME(S) PERFORMED

24 hours, 7 days a week including holidays.

STAT DAY(S) AND TIME(S) PERFORMED

Available

CPT

80162

Method Name

Kinetic Interaction of Microparticles in solution (KIMS)

Reference Values

Adults: 0.8 – 2.0 ng/nL

Reject Due To

Whole blood/unspun samples greater than 6 hours will be
rejected.

Synonyms

N/A

Additional Information

CMS has established a national
coverage policy (NCD) for Medicare for
this test as of November 25, 2002. Please document medical
necessity. 

https://www.cms.gov/medicare-coverage-database/details/ncd-details.aspx?NCDId=103&ncdver=1&bc=AgEAAAAAAAAA

Included in Additional codes

N/A