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Test Code CRP C-Reactive Protein (CRP), Plasma

Specimen Type

Preferred: Plasma

Acceptable: Serum


Preferred: Lithium Heparin (Mint Green or Dark Green)


Acceptable: Serum Red Top tube or Gold SST

Preferred Volume

5 mL

UCMC Collection Instructions

1. Samples need to be received in the lab within 2 hours of collection at room temperature.

2. Greater than 2 hours must be refrigerated at 2-8°C.

3. If the specimen cannot be sent to the lab within 6 hours of collection, it must be spun, aliquoted and refrigerated at 2-8°C.

4. All unspun specimens greater than 6 hours will be rejected.  

5. If above criteria are not met, specimen will be rejected.



Turnaround Time

4 hours

STAT Availability

Not Available

Test Usage

CRP assays are used to detect systemic inflammatory processes; to assess treatment of bacterial infections with antibiotics; to detect intrauterine infections with concomitant premature amniorrhexis; to differentiate between active and inactive forms of disease with concurrent infection;  to determine the presence of post-operative complications at an early stage, such as infected wounds.

Test Methodology

Particle-enhanced immunoturbidimetric assay

Additional Information

Refer to high sensitivity CRP test for use in cardiac risk assessment.

CPT Code


Test Includes

Quantitative determination of CRP in plasma

Test Limitations

Significantly decreased CRP values may be obtained from samples taken from patients who have been treated with carboxypenicillins.

Reference Range

<5.0 mg/L

Critical Results


Fee Code


Minimum Volume

2 mL

Offsite Collection Instuctions

1. Serum and plasma tubes should be centrifuged and aliquoted within 2 hours of collection.

2. Aliquoted samples could either be room temperature at 15-25°C or refrigerated at 2-8°C prior and during transportation.

3. If above criteria are not met, specimen will be rejected.