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Test Code TE Testosterone, Total

Specimen Type

Blood

Container

Red top

Preferred Volume

4 mL

Availability

Tuesday and Friday

Turnaround Time

4 – 5 days

STAT Availability

Not Available

Test Methodology

high-performance liquid chromatography/tandem mass spectrometry (LC-MS/MS)

Additional Information

This test was developed and its performance characteristics determined by the University of Chicago Medical Center, Clinical Chemistry Laboratories in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code

84403

STAT Turnaround Time

Not available

Reference Range

Age-Adjusted Ranges Reference Range (ng/dL)

 

Males

0-5 months 75-400

6 months-9 years <20

10-11 years <130

12-13 years <800

14 years <1,200

15-16 years 100-1,200

17-18 years 300-1,200

19-55 years 240-950§

56-75 years 180-800§

 

Females

0-5 months 20-80

6 months-9 years <20

10-11 years <44

12-16 years 15-60†

17-40 years 20-60†

41-60 <60

 

Post-menopausal (>60 yrs) 5-70§

 

†Female total testosterone reference ranges established in children and women by studies performed at UCMC1,2,3.

§Testosterone data in the elderly are informational, based on radioimmunoassay data.

 

References

 

1. Children: Bordini BD, Littlejohn EE, Rosenfeld RL. J Clin Endocrinol Metab 2009; 94: 1168-1175
2. Women: Mortensen M, Ehrmann DA, Littlejohn E, Rosenfield RL. J Clin Endocrinol Metab 2009; 94: 1579-86
3. Rosenfield RL, Mortensen M, Wroblewski K, Littlejohn E, Ehrmann DA. Determination of the source of androgen excess in functionally atypical polycystic ovary syndrome by a short dexamethasone androgen-suppression test and a low-dose ACTH test. Hum Reprod 2011;26:3138-46

Critical Results

None

Test Limitations

Testosterone levels can fluctuate substantially between different days, and sometimes even more frequently. Assessment of androgen status should be based on more than a single measurement.

Minimum Volume

2 mL

Test Includes

quantitative determination of Total testosterone

Fee Code

43259