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Test Code RNAP RNA Polymerase III Antibodies, IgG, Serum

Reporting Name

RNA Polymerase III Ab, IgG, S

Useful For

Evaluating patients suspected of having systemic sclerosis, when used in conjunction with centromere and Scl70 antibodies


Providing diagnostic and prognostic information in patients with systemic sclerosis

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reference Values

<20.0 U (negative)

20.0-39.9 U (weak positive)

40.0-80.0 U (moderate positive)

>80.0 U (strong positive)

Day(s) and Time(s) Performed


Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
RNAP RNA Polymerase III Ab, IgG, S 79182-2


Result ID Test Result Name Result LOINC Value
RNAP RNA Polymerase III Ab, IgG, S 79182-2

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross OK



Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)