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Test Code LAC Lactate, Plasma

Specimen Type

Blood

Container

Gray top on ice

Preferred Volume

4 mL

Offsite Collection Instructions

Blood should be drawn from a statis-free vein, however, minimal hemostasis (less than 30 seconds) will not affect lactate levels.   Avoid the use of a tourniquet, if possible.  Plasma should be separated from cells within 15 minutes of collection.  Transport at 2-8C.

UCMC Collection Instructions

  • MUST DELIVER ON ICE TO LAB WITHIN 15 MINUTES OF COLLECTION
  • Blood should be drawn from a statis-free vein, however, minimal hemostasis (less than 30 seconds) will not affect lactate levels.
  • Avoid the use of a tourniquet, if possible.

Availability

24/7

Turnaround Time

3 hours

STAT Availability

Available

Test Usage

L-lactate levels that evaluate the acid-base status are used in the diagnosis and treatment of lactic acidosis.

Test Methodology

Spectrophotometric, kinetic

Additional Information

The lactate level increases rapidly with physical exercise. The time required for return to normal lactate values depends on the physical fitness of the subject. 30 minutes at rest is usually sufficient for this purpose.
 

Glycolysis in blood samples can rapidly increase lactate levels. Cells contribute to the glycolysis and their quick removal is essential for accurate lactate analysis.

CPT Code

83605

Test Includes

quantitative determination of L-lactate in plasma

Reference Range

0.7 – 2.1 mEq/L

Critical Results

None

Test Limitations

Dopamine (10 mg/L; 65 nmol/L), Levodopa (20 mg/L; 101 nmol/L) and Methyldopa (20 mg/L; 95 nmol/L) significantly reduced the lactate results. 
 

Glycolate, a metabolite of ethylene glycol, causes a positive interference which is variable from lot to lot of reagent.

STAT Turnaround Time

1 hour

Minimum Volume

2 mL

Fee Code

43526