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Test Code AHPNL Acute Hepatitis Panel, Serum

Biohazard Infectious

Specimen Type



Serum Red Top tube or Gold SST

Preferred Volume

5 mL

Offsite Collection Instructions

1. Serum should be centrifuged and aliquoted within 2 hours of collection.

2. Aliquoted samples should be refrigerated at 2-8°C prior and during transportation.

3. If above criteria are not met, specimen will be rejected.

4. Li-Heparin tubes will be rejected.

UCMC Collection Instructions

1. Samples need to be received in the lab within 2 hours of collection at room temperature.

2. Greater than 2 hours must be refrigerated at 2-8°C.

3. If the specimen cannot be sent to the lab within 6 hours of collection, it must be spun, aliquoted and refrigerated at 2-8°C 

4. All unspun samples greater than 6 hours will rejected.

5. If above criteria are not met, specimen will be rejected.

6. Li-Heparin tubes will be rejected.



Turnaround Time

4 hours

STAT Availability

Not Available

Test Usage

Once per admit when liver function tests are abnormal or before transplant.

Test Methodology

Electrochemiluminescence Immunoassay (ECLIA)

CPT Code


Test Limitations

Confirmation of specimens repeatedly reactive for hepatitis C antibody recommended  by HCV antibody neutralization or RIBA (recombinant immunoblot assay). 

Coverage Information

CMS has established a national coverage policy (NCD) for Medicare for this test as of November 25, 2002. Please document medical necessity. For more details click this link:ncd-details.aspx

Reference Range

HBCM, HAABM & HCVAB:  Non reactive                                      HBSAG: Non reactive


                                              Borderline                                                         Reactive






Refer to individual test listings for additional information.

Fee Code


Minimum Volume

2 mL

Test Includes

Acute Hepatitis Panel (CPT 80074) includes four tests: Hepatitis A IgM antibody (HAABM), Hepatitis B core IgM antibody (HBCM), Hepatitis B surface antigen (HBSAG), Hepatitis C antibody (HCVAB).  Each of these may be ordered individually. A test or panel may be ordered only when all components are medically necessary to diagnose or treat an individual patient.  If all components are not medically necessary, a less inclusive panel and/or an individual test as appropriate to treat the individual patient should be ordered.